BreakOUT Game Group 2

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Hi, welcome to our game, in this challenge there will be various questions and riddles concerning two important female scientists.We hope that you will enjoy our work. Good luck and have fun!

GenialBreakout

04 Follow the series

03 Correct image

02 Find!

01 Quiz

Reward

Introduction

Collect all the numbers by completing each of the challenges, and enter them in order in the final section to finish the game.

Index

JENNIFER DOUDNA

ROSALIND FRANKLIN

INTRODUCTION

Return

ROSALIND FRANKLIN ,THE WOMAN THAT CONTRIBUTED TO THE DISCOVERY OF THE STRUCTURE OF DNA. British chemist Rosalind Franklin, born in 1920 in Notting Hill, and in 1942 she brought her physics and chemistry expertise to London Coal, where she investigated the properties of carbon. This was crucial to the war effort, which relied on coal and carbon for strategic equipment like gas masks. This research was the basis of her PhD thesis at Cambridge. In 1950 during her research she discovered that there were two forms of DNA and was offered a three-year scholarship to undertake further investigation at King’s College in London. Here she deduced the basic dimensions of DNA strands and the likely helical structure. She also found that when DNA is exposed to high levels of moisture, its structure changed. The ExoFit model of the Rosalind Franklin rover is manoeuvered over the surface of the Atacama Desert by mission control, 11,000km away in the UK © ESA A model of the rover bearing Rosalind Franklin’s name © ESA In 1953, her colleague Maurice Wilkins showed James Watson and Francis Crick the X-ray data that Rosalind had obtained, confirming the 3D structure that the pair had speculated about for DNA. In March 1958 Rosalind passed away at the age of 37 from several illnesses, including ovarian cancer. In 1962, the Nobel Prize in Physiology or Medicine was awarded to James Watson, Francis Crick and Maurice Wilkins for solving the structure of DNA. Watson suggested that Rosalind, along with Wilkins, should be awarded a Nobel Prize for Chemistry, but the Nobel Committee does not make posthumous nominations. In his 1968 book, The Double Helix, Watson outlined how the two had become friends while working together. He also remarked that he would never have won a Nobel Prize or published a famous paper if it wasn’t for Rosalind. – John S Croucher

Return

JENNIFER DOUDNA(IN THE PRESENT). The inventor of a groundbreaking technology for editing genomes, named CRISPR-Cas9, Jennifer Doudna is one of the greatest living scientists. Allowing scientists to make ultra-precise edits to DNA in cells, it could potentially help to cure genetic deformities and diseases — including cancer. Studies have shown that CRISPR technology can be used to alter the DNA of the HIV virus in human cells. It was also used successfully in 2016, when two monkey twins were born healthy but with specific genetic mutations. Whilst this is indeed revolutionary, it does cause some serious ethical concerns. Most notably if it is used on humans. This actually happened in China — where researchers experimented with CRISPR technology on human embryos. In the wrong hands, CRISPR could be used to create so- called “designer babies.” Whilst this is potentially an uneasy future for the technology, if used in the right way, CRISPR could help us cure cell diseases previously thought incurable. And it is Jennifer Doudna, one of the greatest living female scientists, who will have made it possible.

Complete the following quiz, and getthe first number towards your reward!

QUIZ

start

March 1958

May 1920

April 1947

When did Rosalind Franklin die?

question 1/3

QUIZ

QUIZ

RIGHT!

next

QUIZ

She discovered X-rays

She discovered the structure of the cell

She discovered the structure of DNA

What did Rosalind Franklin discover?

question 2/3

QUIZ

RIGHT!

NEXT

It is a medicine that cure cancer.

QUIZ

It works as a painkiller.

It edits DNA

What does CRISPR-CAS9 technology do?

QUESTION 3/3

QUIZ

RIGHT!

NEXT

QUIZ

RIGHT!

NEXT

QUIZ

TRY AGAIN

ERROR!

START

From among all the statements you discover,click only on the correct ones

FIND!

True

False

You can drag the light to search through the darkness

Rosalind Franklin was British.

The CRISPR CAS9 techlonogy was used in 2016 on 2 monkeys.

The DNA was discovered by Mendel.

The CRISPR CAS9 was invented by a French scientist.

You can drag the light to search through the darkness

CLICK ONLY ON THE CORRECT STATEMENT

TRY AGAIN

Wrong! That statement is incorrect

ERROR!

start

Choose the correct image

CORRECT IMAGE

which of these two images is related to the research of the two scientists?

which one of these images is the CRISPR-CAS9 technology

RIGHT!

wHO IS ROsalind franklin?

RIGHT!

TRY AGAIN

ERROR!

Choose the correct shape in the series

serieS

START

Option 06

Option 05

Option 04

Option 03

Option 02

Option 01

Choose the correct shape:

WHAT SHAPE GOES NEXT?

RIGHT!

Option 05

Option 04

Option 03

Option 02

Option 01

Choose the correct shape:

WHAT SHAPE GOES NEXT?

Option 06

Option 05

Option 04

Option 03

Option 02

Option 01

Choose the correct shape:

RIGHT!

WHAT SHAPE GOES NEXT?

TRY AGAIN

ERROR!

ERROR!

BACK TO INDEX

THE FIRST NUMBER IS:

GREAT!

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THE SECOND NUMBER IS:

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THE THIRD NUMBER IS:

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THE FOURTH NUMBER IS:

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