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Side effects of CAR-T cell therapy:

Alice Reynolds

Created on March 23, 2026

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Transcript

Side effects of CAR-T cell therapy:

CAR-T cells can affect the brain, leading to:

  • confusion
  • headaches
  • seizures
  • difficulty speaking

An intense immune reaction where large amounts of cytokines are released, causing fever, low blood pressure, and organ dysfunction.

CAR-T cells also destroy normal B cells, weakening the immune system and increasing susceptibility to infections.

Low levels of blood cells (red cells, platelets, neutrophils) can persist after treatment causing:

  • fatigue
  • bleeding
  • infection risk