Guess the ANA Pattern!
(AC-23) Rods and Rings
(AC-25) Spindle Fibers
(AC-22) Polar / Golgi-Like
(AC-23) Rods and rings
- The Rods and Rings (RR) pattern is a distinctive cytoplasmic pattern seen on HEp-2 cells and characterized by elongated rod-like structures (linear, smooth filaments) and circular or annular ring-shaped structures, vafrying in length and orientation. Typically with 1-5 structures per cell located in the cytoplasm (not in the nucleus).
- Antigens: The principal autoantigen associated with RR is inosine monophosphate dehydrogenase type 2 (IMPDH2).
- Associated Diseases: Hepatitis C has the strongest and most well-established association with RR.
Learn More about Hepatitis C
Learn about theSebia IFA ANA Solutions
Back
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This pattern is NOT Spindle Fibers. Please try again.
Associated Diseases
Hepatitis C Hepatitis C is a liver disease caused by the hepatitis C virus (HCV). It can range from a mild illness lasting a few weeks to a serious, long-term illness. Left untreated, hepatitis C can lead to serious liver problems, like scarring and cancer. Many people with hepatitis C don't look or feel sick so might not know they have the virus! If you do develop symptoms, you will notice them 2-12 weeks after infection with the virus. Symptoms can include dark urine or clay-colored stools, feeling tired, fever, joint pain, loss of appetite, nausea, stomach pain, throwing up, or jaundice. Most people can be cured of hepatitis C with timely treatment.If you don't get treatment, you can develop chronic liver disease even if you don't have any symptoms for years.
https://www.cdc.gov/hepatitis-c/about/index.html
Sebia IFA ANA Solutions
Antinuclear antibody (ANA) immunofluorescent testing aids in diagnosing lupus and monitors treatment progress through titer regression.* As a pioneer in immunofluorescence assay (IFA) technology, Sebia continually delivers quality and expertise in autoimmune serology that laboratories have relied upon since 1976. Our proprietary cell fixation process allows users to work with cells containing natural, unaltered antigens, resulting in simplified, easy-to-read patterns.
Sebia dIFine® Automated Family
Sebia is taking your ANA IFA testing to the next level by pairing our top tier IFA ANA HEp-2 slides with our dIFine® family, inlcuding our P30 processor and our automated microscope, the next generation in IFA imaging and pattern recognition.
Oops!
This pattern is NOT Polar / Golgi-Like. Please try again.
Guess the Pattern - Week 3 - 2026
Melissa Cifuentes
Created on March 4, 2026
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Transcript
Guess the ANA Pattern!
(AC-23) Rods and Rings
(AC-25) Spindle Fibers
(AC-22) Polar / Golgi-Like
(AC-23) Rods and rings
Learn More about Hepatitis C
Learn about theSebia IFA ANA Solutions
Back
Oops!
This pattern is NOT Spindle Fibers. Please try again.
Associated Diseases
Hepatitis C Hepatitis C is a liver disease caused by the hepatitis C virus (HCV). It can range from a mild illness lasting a few weeks to a serious, long-term illness. Left untreated, hepatitis C can lead to serious liver problems, like scarring and cancer. Many people with hepatitis C don't look or feel sick so might not know they have the virus! If you do develop symptoms, you will notice them 2-12 weeks after infection with the virus. Symptoms can include dark urine or clay-colored stools, feeling tired, fever, joint pain, loss of appetite, nausea, stomach pain, throwing up, or jaundice. Most people can be cured of hepatitis C with timely treatment.If you don't get treatment, you can develop chronic liver disease even if you don't have any symptoms for years.
https://www.cdc.gov/hepatitis-c/about/index.html
Sebia IFA ANA Solutions
Antinuclear antibody (ANA) immunofluorescent testing aids in diagnosing lupus and monitors treatment progress through titer regression.* As a pioneer in immunofluorescence assay (IFA) technology, Sebia continually delivers quality and expertise in autoimmune serology that laboratories have relied upon since 1976. Our proprietary cell fixation process allows users to work with cells containing natural, unaltered antigens, resulting in simplified, easy-to-read patterns.
Sebia dIFine® Automated Family
Sebia is taking your ANA IFA testing to the next level by pairing our top tier IFA ANA HEp-2 slides with our dIFine® family, inlcuding our P30 processor and our automated microscope, the next generation in IFA imaging and pattern recognition.
Oops!
This pattern is NOT Polar / Golgi-Like. Please try again.