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SAST_M3_VKC_C&C_Melanoma. Staging, Local Control

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Transcript

These readings examine melanoma in dogs (and more cautiously cats), focusing on what is broadly agreed and what remains uncertain in everyday clinical decisions. Together, they show why clinician advice differs, particularly on staging extent, the practical meaning of curative-intent surgery, and how to advise owners on adjuvant systemic therapy when evidence is limited or inconsistent.

Efficacy of systemic adjuvant therapies administered to dogs after excision of oral malignant melanomas: 151 cases (2001–2012)

Outcome following curative-intent surgery for oral melanoma in dogs: 70 cases (1998–2011)

Sarah E. Boston (et al)

Joanne L. Tuohy (et al)

Gerry Polton (et al)

Melanoma of the dog and cat: consensus and guidelines

Outcome following curative-intent surgery for oral melanoma in dogs: 70 cases (1998–2011)

Joanne L. Tuohy (et al)

Joanne L. Tuohy (et al)

Outcome following curative-intent surgery for oral melanoma in dogs: 70 cases (1998–2011)

Journal of the American Veterinary Medical Association (JAVMA)

Synopsis

This retrospective study of 70 dogs with oral melanoma shows that curative-intent surgery yields a median survival of 723 days. While metastasis and large tumor size reduce survival times, thorough local surgical control remains the cornerstone for achieving long-term outcomes.

Publication date:

11/12/2024

Pages:

08

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Melanoma of the dog and cat: consensus and guidelines

Gerry Polton (et al)

Gerry Polton (et al)

Frontiers in Veterinary Science

Melanoma of the dog and cat: consensus and guidelines

Synopsis

These guidelines consolidate current knowledge on canine and feline melanoma, recommending wide surgical resection as the primary treatment, often integrated with radiotherapy and immunotherapy to improve survival and quality of life.

Publication date:

05/04/2024

Pages:

14

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Efficacy of systemic adjuvant therapies administered to dogs after excision of oral malignant melanomas: 151 cases (2001–2012)

Sarah E. Boston (et al)

Sarah E. Boston (et al)

Efficacy of systemic adjuvant therapies administered to dogs after excision of oral malignant melanomas: 151 cases (2001–2012)

Journal of the American Veterinary Medical Association (JAVMA)

Synopsis

This retrospective study of 151 dogs with oral malignant melanoma found an overall median survival time of 346 days, identifies tumor size, age, and complete surgical excision as key prognostic factors. Crucially, the analysis revealed no significant survival benefit from systemic adjuvant therapies, such as chemotherapy or vaccination, when compared to surgery alone, highlighting the paramount importance of local surgical control.

Publication date:

15/08/2014

Pages:

07

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