In this module, we explore the core principles of oncological surgery, focusing on accurate diagnosis, appropriate surgical planning, and effective tumour resection. Margin selection, staging, pathology interpretation, and adjunct therapies influence outcomes, while recognising species- and tumour-specific considerations and when specialist referral is required.
Anaesthesia in Veterinary Oncology: The Effects of Surgery,
Volatile and Intravenous Anaesthetics on the Immune System
and Tumour Spread
Ana Vidal Pinheiro (et al)
Optical coherence tomography for surgical margin evaluation
of excised canine cutaneous and subcutaneous tumours
Scar revision for incompletely or narrowly excised soft tissue sarcomas
in dogs
Edward Cheng (et al)
Janet A. Grimes (et al)
The effectiveness of using dye models for small tissue
biopsies in the surgical pathology laboratory
Predaporn Nonsiri (et al)
Gerry Polton (et al)
Melanoma of the dog and cat:
consensus and guidelines
In this module, we explore the core principles of oncological surgery, focusing on accurate diagnosis, appropriate surgical planning, and effective tumour resection. Margin selection, staging, pathology interpretation, and adjunct therapies influence outcomes, while recognising species- and tumour-specific considerations and when specialist referral is required.
Efficacy of systemic adjuvant therapies
administered to dogs after excision of oral
malignant melanomas: 151 cases (2001–2012)
Outcome following curative-intent surgery
for oral melanoma in dogs:
70 cases (1998–2011)
Sarah E. Boston (et al)
Joanne L. Tuohy (et al)
Radical excision with five-centimeter margins
for treatment of feline injection-site sarcomas:
91 cases (1998–2002)
Holly A. Phelps (et al)
Mast Cell Tumors in Cats - Clinical update and possible
new treatment avenues
Carolyn Henry (et al)
Laura E. Selmic (et al)
A systematic review of surgical margins
utilized for removal of cutaneous mast cell
tumors in dogs
In this module, we explore the core principles of oncological surgery, focusing on accurate diagnosis, appropriate surgical planning, and effective tumour resection. Margin selection, staging, pathology interpretation, and adjunct therapies influence outcomes, while recognising species- and tumour-specific considerations and when specialist referral is required.
Canine Subcutaneous Mast Cell Tumour: Characterisation and Prognostic Indices
Feline Injection-Site Sarcoma: Matrix Remodelling and Prognosis
J. J. Thompson (et al)
I. Porcellato (et al)
Histologic Grading of Canine Mast
Cell Tumor: Is 2 Better Than 3?
S. Sabattini (et al)
Histiocytic Sarcoma and Hemangiosarcoma Update
Christine Mullin (et al)
A. Matsuyama (et al)
Impact of surgical margins on survival of 37 dogs with massive hepatocellular carcinoma
In this module, we explore the core principles of oncological surgery, focusing on accurate diagnosis, appropriate surgical planning, and effective tumour resection. Margin selection, staging, pathology interpretation, and adjunct therapies influence outcomes, while recognising species- and tumour-specific considerations and when specialist referral is required.
Soft Tissue Sarcoma in the Dog – Part 1: A Current Review
Treatment outcomes and prognostic factors of feline splenic mast cell tumours: A multi-institutional retrospective study of 64 cases
J. P. Bray
B. J. Evans (et al)
Prognostic Factors for Cutaneous and Subcutaneous Soft Tissue Sarcomas in Dogs
M. M. Dennis (et al)
Urologic Oncology
Kristine Elaine Burgess (et al)
Treatment outcomes and prognostic factors of feline splenic mast cell tumours: A multi-institutional retrospective study of 64 cases
B. J. Evans (et al)
Treatment outcomes and prognostic factors of feline splenic mast cell tumours: A multi-institutional retrospective study of 64 cases
B. J. Evans (et al)
Veterinary and Comparative Oncology
Synopsis
Splenectomy is the treatment of choice for feline splenic mast cell tumors, significantly prolonging survival (856 vs. 342 days). This study of 64 cats found no additional benefit from adjuvant chemotherapy and identified no significant prognostic factors influencing clinical outcomes.
Publication date:
2017
Pages:
13
Listen
Read
Feline Injection-Site Sarcoma: Matrix Remodelling and Prognosis
I. Porcellato (et al)
Veterinary Pathology
I. Porcellato (et al)
Feline Injection-Site Sarcoma: Matrix Remodelling and Prognosis
Synopsis
This study on feline injection-site sarcoma (FISS) found that immunohistochemical markers such as MMP-2, MMP-9, and TIMP-2 do not reliably predict clinical outcomes despite their role in tumour invasiveness. Instead, tumour size (exceeding 3.75 cm) and mitotic count (over 20 mitoses per 10 high-power fields) emerged as the most significant indicators of recurrence and survival. These findings suggest that traditional metrics of tumour dimensions and cellular proliferation remain the most effective tools for assessing prognosis in cats with FISS.
Publication date:
2017
Pages:
16
Listen
Read
Canine Subcutaneous Mast Cell Tumour: Characterisation and Prognostic Indices
J. J. Thompson (et al)
Veterinary Pathology
J. J. Thompson (et al)
Canine Subcutaneous Mast Cell Tumour: Characterisation and Prognostic Indices
Synopsis
This study of 306 dogs reveals that canine subcutaneous mast cell tumours carry a highly favourable prognosis, with low rates of recurrence and metastasis even following incomplete surgical excision. The mitotic index (MI) is the primary prognostic indicator, as an MI greater than four significantly correlates with reduced survival. These findings suggest that subcutaneous tumours should be evaluated independently from cutaneous variants, as they typically exhibit less aggressive biological behaviour and prolonged survival times.
Publication date:
01/2011
Pages:
09
Listen
Read
Histiocytic Sarcoma and Hemangiosarcoma Update
Christine Mullin, Craig A. Clifford
Veterinary Clinics of North America: Small Animal Practice
Christine Mullin (et al)
Histiocytic Sarcoma and Hemangiosarcoma Update
Synopsis
This update examines histiocytic sarcoma and hemangiosarcoma, focusing on breed predispositions and current treatments. While multimodal therapy has significantly improved survival for localized histiocytic sarcoma, visceral hemangiosarcoma remains highly aggressive and typically fatal, highlighting the ongoing clinical challenge of managing these metastatic malignancies.
Publication date:
2019
Pages:
22
Listen
Read
Melanoma of the dog and cat:
consensus and guidelines
Gerry Polton (et al)
Frontiers in Veterinary Science
Gerry Polton (et al)
Melanoma of the dog and cat: consensus and guidelines
Synopsis
These guidelines consolidate current knowledge on canine and feline melanoma, recommending wide surgical resection as the primary treatment, often integrated with radiotherapy and immunotherapy to improve survival and quality of life.
Publication date:
05/04/2024
Pages:
14
Listen
Read
Impact of surgical margins on survival of 37 dogs with massive hepatocellular carcinoma
A. Matsuyama (et al)
A. Matsuyama (et al)
New Zealand Veterinary Journal
Impact of surgical margins on survival of 37 dogs with massive hepatocellular carcinoma
Synopsis
In dogs with massive hepatocellular carcinoma, complete surgical resection significantly improves both progression-free and overall survival compared to incomplete excision. While complete margins are ideal for long-term prognosis, dogs with incomplete margins still maintain a median survival of over two years but require diligent monitoring for local recurrence.
Publication date:
26/04/2017
Pages:
09
Listen
Read
Soft Tissue Sarcoma in the Dog – Part 1: A Current Review
J. P. Bray
Journal of Small Animal Practice (JSAP)
J. P. Bray
Soft Tissue Sarcoma in the Dog – Part 1: A Current Review
Synopsis
Canine soft tissue sarcomas are common mesenchymal tumors where histological grade serves as the primary prognostic indicator. While wide surgical margins remain the traditional standard, this review highlights that treatment is increasingly tailored based on tumor aggressiveness, as complete resection is essential for preventing local recurrence and managing the higher metastatic risk associated with high-grade cases.
Publication date:
2016
Pages:
25
Listen
Read
Prognostic Factors for Cutaneous and Subcutaneous Soft Tissue Sarcomas in Dogs
M. M. Dennis (et al)
Veterinary Pathology (ACVP / ECVP / JCVP; SAGE Publications)
M. M. Dennis (et al)
Prognostic Factors for Cutaneous and Subcutaneous Soft Tissue Sarcomas in Dogs
Synopsis
Histologic grade and surgical margin completeness are the primary prognostic indicators for canine soft tissue sarcomas, with a high mitotic index significantly correlating with reduced survival. While most cases have a favorable prognosis following excision, grade III tumors carry the highest risk of metastasis, necessitating standardized classification and rigorous research to improve clinical outcomes.
Publication date:
01/2011
Pages:
10
Listen
Read
Urologic Oncology
Kristine Elaine Burgess, Carol J. DeRegis
Veterinary Clinics of North America: Small Animal Practice
Kristine Elaine Burgess (et al)
Synopsis
Urologic Oncology
This review addresses the diagnosis and management of rare primary renal tumors and more common transitional cell carcinomas (TCC) in dogs and cats. It highlights the prognostic importance of the mitotic index in renal cell carcinoma and underscores a multimodal treatment strategy for TCC, incorporating advanced diagnostics like BRAF mutation testing, COX-2 inhibitors, and palliative interventional surgery to manage urinary obstructions.
Publication date:
02/2023
Pages:
10
Listen
Read
Optical coherence tomography for surgical margin evaluation
of excised canine cutaneous and subcutaneous tumours
Edward Cheng (et al)
Optical coherence tomography for surgical margin evaluation of excised canine cutaneous and subcutaneous tumours
Edward Cheng (et al)
Veterinary and Comparative Oncology
Synopsis
This study demonstrates that optical coherence tomography (OCT) is a highly effective tool for real-time surgical margin evaluation in canine skin tumors, achieving a median sensitivity of 86.7% and specificity of 84.6% in detecting incomplete margins compared to histopathology.
Publication date:
01/06/2022
Pages:
10
Listen
Read
Radical excision with five-centimeter margins
for treatment of feline injection-site sarcomas:
91 cases (1998–2002)
Holly A. Phelps (et al)
Holly A. Phelps (et al)
Radical excision with five-centimeter margins for treatment of feline injection-site sarcomas: 91 cases (1998–2002)
Journal of the American Veterinary Medical Association (JAVMA)
Synopsis
This study demonstrates that radical excision with five-centimeter margins significantly improves survival times (901-day median) and reduces local recurrence rates (14%) for feline injection-site sarcomas compared to traditional surgical approaches.
Publication date:
01/07/2011
Pages:
10
Listen
Read
Histologic Grading of Canine Mast
Cell Tumor: Is 2 Better Than 3?
S. Sabattini, F. Scarpa, D. Berlato, Bettini
Veterinary Pathology
S. Sabattini (et al)
Histologic Grading of Canine Mast
Cell Tumor: Is 2 Better Than 3?
Synopsis
This study demonstrates that the Kiupel 2-tier system is superior to the Patnaik 3-tier system for predicting survival in canine mast cell tumors. By identifying high-risk cases within the ambiguous Patnaik grade II category, the 2-tier system provides better prognostic clarity and more effective guidance for clinical management.
Publication date:
01/2015
Pages:
04
Listen
Read
A systematic review of surgical margins
utilized for removal of cutaneous mast cell
tumors in dogs
Laura E. Selmic, Audrey Ruple
Laura E. Selmic (et al)
BMC Veterinary Research
A systematic review of surgical margins utilized for removal of cutaneous mast cell tumors in dogs
Synopsis
This systematic review suggests that 2 cm lateral margins and one fascial plane deep provide effective local control for Patnaik grade I and II canine mast cell tumors smaller than 4 cm, resulting in low rates of recurrence and incomplete excision.
Publication date:
2020
Pages:
06
Listen
Read
Efficacy of systemic adjuvant therapies
administered to dogs after excision of oral
malignant melanomas: 151 cases (2001–2012)
Sarah E. Boston (et al)
Sarah E. Boston (et al)
Efficacy of systemic adjuvant therapies administered to dogs after excision of oral malignant melanomas: 151 cases (2001–2012)
Journal of the American Veterinary Medical Association (JAVMA)
Synopsis
This retrospective study of 151 dogs with oral malignant melanoma found an overall median survival time of 346 days, identifies tumor size, age, and complete surgical excision as key prognostic factors. Crucially, the analysis revealed no significant survival benefit from systemic adjuvant therapies, such as chemotherapy or vaccination, when compared to surgery alone, highlighting the paramount importance of local surgical control.
Publication date:
15/08/2014
Pages:
07
Listen
Read
The effectiveness of using dye models for small tissue
biopsies in the surgical pathology laboratory
Predaporn Nonsiri (et al)
Predaporn Nonsiri (et al)
Folia Histochemica et Cytobiologica
The effectiveness of using dye models for small tissue biopsies in the surgical pathology laboratory
Synopsis
This study identifies hematoxylin as an ideal, non-toxic tissue marking dye that significantly improves the visibility of small biopsies (0.2–0.3 cm) during laboratory processing without interfering with pathological diagnosis.
Publication date:
12/06/2023
Pages:
07
Listen
Read
Anaesthesia in Veterinary Oncology: The Effects of Surgery,
Volatile and Intravenous Anaesthetics on the Immune System
and Tumour Spread
Ana Vidal Pinheiro (et al)
Anaesthesia in Veterinary Oncology: The Effects of Surgery, Volatile and Intravenous Anaesthetics on the Immune System and Tumour Spread
Ana Vidal Pinheiro (et al)
University of Trás-os-Montes e Alto Douro
Synopsis
This review suggests that while surgical stress and volatile anaesthetics suppress immunity and may promote metastasis, propofol displays immunoprotective properties. Consequently, Total Intravenous Anaesthesia (TIVA) combined with regional analgesia is recommended to minimise disease recurrence in veterinary oncology.
Publication date:
01/11/2023
Pages:
17
Listen
Read
Outcome following curative-intent surgery
for oral melanoma in dogs:
70 cases (1998–2011)
Joanne L. Tuohy (et al)
Joanne L. Tuohy (et al)
Journal of the American Veterinary Medical Association (JAVMA)
Outcome following curative-intent surgery for oral melanoma in dogs: 70 cases (1998–2011)
Synopsis
This retrospective study of 70 dogs with oral melanoma shows that curative-intent surgery yields a median survival of 723 days. While metastasis and large tumor size reduce survival times, thorough local surgical control remains the cornerstone for achieving long-term outcomes.
Publication date:
11/12/2024
Pages:
08
Listen
Read
MAST CELL TUMORS IN CATS
- Clinical update and possible
new treatment avenues
Carolyn Henry, Chamisa Herrera
Journal of Feline Medicine and Surgery
Carolyn Henry (et al)
Mast Cell Tumors in Cats - Clinical update and possible new treatment avenues
Synopsis
This review summarizes feline mast cell tumor management, highlighting that while cutaneous lesions typically carry a good prognosis after surgery, visceral forms require thorough staging and may benefit from systemic treatments like tyrosine kinase inhibitors.
Publication date:
2013
Pages:
07
Listen
Read
Scar revision for incompletely or narrowly excised soft tissue sarcomas
in dogs
Janet A. Grimes (et al)
The Canadian Veterinary Journal (CVJ)
Janet A. Grimes (et al)
Scar revision for incompletely or narrowly excised soft tissue sarcomas in dogs
Synopsis
This study shows that scar revision for canine soft tissue sarcomas with inadequate margins is highly effective, resulting in a local recurrence rate of only 3.0% and providing durable tumor remission.
Publication date:
01/2023
Pages:
06
Listen
Read
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Transcript
In this module, we explore the core principles of oncological surgery, focusing on accurate diagnosis, appropriate surgical planning, and effective tumour resection. Margin selection, staging, pathology interpretation, and adjunct therapies influence outcomes, while recognising species- and tumour-specific considerations and when specialist referral is required.
Anaesthesia in Veterinary Oncology: The Effects of Surgery, Volatile and Intravenous Anaesthetics on the Immune System and Tumour Spread
Ana Vidal Pinheiro (et al)
Optical coherence tomography for surgical margin evaluation of excised canine cutaneous and subcutaneous tumours
Scar revision for incompletely or narrowly excised soft tissue sarcomas in dogs
Edward Cheng (et al)
Janet A. Grimes (et al)
The effectiveness of using dye models for small tissue biopsies in the surgical pathology laboratory
Predaporn Nonsiri (et al)
Gerry Polton (et al)
Melanoma of the dog and cat: consensus and guidelines
In this module, we explore the core principles of oncological surgery, focusing on accurate diagnosis, appropriate surgical planning, and effective tumour resection. Margin selection, staging, pathology interpretation, and adjunct therapies influence outcomes, while recognising species- and tumour-specific considerations and when specialist referral is required.
Efficacy of systemic adjuvant therapies administered to dogs after excision of oral malignant melanomas: 151 cases (2001–2012)
Outcome following curative-intent surgery for oral melanoma in dogs: 70 cases (1998–2011)
Sarah E. Boston (et al)
Joanne L. Tuohy (et al)
Radical excision with five-centimeter margins for treatment of feline injection-site sarcomas: 91 cases (1998–2002)
Holly A. Phelps (et al)
Mast Cell Tumors in Cats - Clinical update and possible new treatment avenues
Carolyn Henry (et al)
Laura E. Selmic (et al)
A systematic review of surgical margins utilized for removal of cutaneous mast cell tumors in dogs
In this module, we explore the core principles of oncological surgery, focusing on accurate diagnosis, appropriate surgical planning, and effective tumour resection. Margin selection, staging, pathology interpretation, and adjunct therapies influence outcomes, while recognising species- and tumour-specific considerations and when specialist referral is required.
Canine Subcutaneous Mast Cell Tumour: Characterisation and Prognostic Indices
Feline Injection-Site Sarcoma: Matrix Remodelling and Prognosis
J. J. Thompson (et al)
I. Porcellato (et al)
Histologic Grading of Canine Mast Cell Tumor: Is 2 Better Than 3?
S. Sabattini (et al)
Histiocytic Sarcoma and Hemangiosarcoma Update
Christine Mullin (et al)
A. Matsuyama (et al)
Impact of surgical margins on survival of 37 dogs with massive hepatocellular carcinoma
In this module, we explore the core principles of oncological surgery, focusing on accurate diagnosis, appropriate surgical planning, and effective tumour resection. Margin selection, staging, pathology interpretation, and adjunct therapies influence outcomes, while recognising species- and tumour-specific considerations and when specialist referral is required.
Soft Tissue Sarcoma in the Dog – Part 1: A Current Review
Treatment outcomes and prognostic factors of feline splenic mast cell tumours: A multi-institutional retrospective study of 64 cases
J. P. Bray
B. J. Evans (et al)
Prognostic Factors for Cutaneous and Subcutaneous Soft Tissue Sarcomas in Dogs
M. M. Dennis (et al)
Urologic Oncology
Kristine Elaine Burgess (et al)
Treatment outcomes and prognostic factors of feline splenic mast cell tumours: A multi-institutional retrospective study of 64 cases
B. J. Evans (et al)
Treatment outcomes and prognostic factors of feline splenic mast cell tumours: A multi-institutional retrospective study of 64 cases
B. J. Evans (et al)
Veterinary and Comparative Oncology
Synopsis
Splenectomy is the treatment of choice for feline splenic mast cell tumors, significantly prolonging survival (856 vs. 342 days). This study of 64 cats found no additional benefit from adjuvant chemotherapy and identified no significant prognostic factors influencing clinical outcomes.
Publication date:
2017
Pages:
13
Listen
Read
Feline Injection-Site Sarcoma: Matrix Remodelling and Prognosis
I. Porcellato (et al)
Veterinary Pathology
I. Porcellato (et al)
Feline Injection-Site Sarcoma: Matrix Remodelling and Prognosis
Synopsis
This study on feline injection-site sarcoma (FISS) found that immunohistochemical markers such as MMP-2, MMP-9, and TIMP-2 do not reliably predict clinical outcomes despite their role in tumour invasiveness. Instead, tumour size (exceeding 3.75 cm) and mitotic count (over 20 mitoses per 10 high-power fields) emerged as the most significant indicators of recurrence and survival. These findings suggest that traditional metrics of tumour dimensions and cellular proliferation remain the most effective tools for assessing prognosis in cats with FISS.
Publication date:
2017
Pages:
16
Listen
Read
Canine Subcutaneous Mast Cell Tumour: Characterisation and Prognostic Indices
J. J. Thompson (et al)
Veterinary Pathology
J. J. Thompson (et al)
Canine Subcutaneous Mast Cell Tumour: Characterisation and Prognostic Indices
Synopsis
This study of 306 dogs reveals that canine subcutaneous mast cell tumours carry a highly favourable prognosis, with low rates of recurrence and metastasis even following incomplete surgical excision. The mitotic index (MI) is the primary prognostic indicator, as an MI greater than four significantly correlates with reduced survival. These findings suggest that subcutaneous tumours should be evaluated independently from cutaneous variants, as they typically exhibit less aggressive biological behaviour and prolonged survival times.
Publication date:
01/2011
Pages:
09
Listen
Read
Histiocytic Sarcoma and Hemangiosarcoma Update
Christine Mullin, Craig A. Clifford
Veterinary Clinics of North America: Small Animal Practice
Christine Mullin (et al)
Histiocytic Sarcoma and Hemangiosarcoma Update
Synopsis
This update examines histiocytic sarcoma and hemangiosarcoma, focusing on breed predispositions and current treatments. While multimodal therapy has significantly improved survival for localized histiocytic sarcoma, visceral hemangiosarcoma remains highly aggressive and typically fatal, highlighting the ongoing clinical challenge of managing these metastatic malignancies.
Publication date:
2019
Pages:
22
Listen
Read
Melanoma of the dog and cat: consensus and guidelines
Gerry Polton (et al)
Frontiers in Veterinary Science
Gerry Polton (et al)
Melanoma of the dog and cat: consensus and guidelines
Synopsis
These guidelines consolidate current knowledge on canine and feline melanoma, recommending wide surgical resection as the primary treatment, often integrated with radiotherapy and immunotherapy to improve survival and quality of life.
Publication date:
05/04/2024
Pages:
14
Listen
Read
Impact of surgical margins on survival of 37 dogs with massive hepatocellular carcinoma
A. Matsuyama (et al)
A. Matsuyama (et al)
New Zealand Veterinary Journal
Impact of surgical margins on survival of 37 dogs with massive hepatocellular carcinoma
Synopsis
In dogs with massive hepatocellular carcinoma, complete surgical resection significantly improves both progression-free and overall survival compared to incomplete excision. While complete margins are ideal for long-term prognosis, dogs with incomplete margins still maintain a median survival of over two years but require diligent monitoring for local recurrence.
Publication date:
26/04/2017
Pages:
09
Listen
Read
Soft Tissue Sarcoma in the Dog – Part 1: A Current Review
J. P. Bray
Journal of Small Animal Practice (JSAP)
J. P. Bray
Soft Tissue Sarcoma in the Dog – Part 1: A Current Review
Synopsis
Canine soft tissue sarcomas are common mesenchymal tumors where histological grade serves as the primary prognostic indicator. While wide surgical margins remain the traditional standard, this review highlights that treatment is increasingly tailored based on tumor aggressiveness, as complete resection is essential for preventing local recurrence and managing the higher metastatic risk associated with high-grade cases.
Publication date:
2016
Pages:
25
Listen
Read
Prognostic Factors for Cutaneous and Subcutaneous Soft Tissue Sarcomas in Dogs
M. M. Dennis (et al)
Veterinary Pathology (ACVP / ECVP / JCVP; SAGE Publications)
M. M. Dennis (et al)
Prognostic Factors for Cutaneous and Subcutaneous Soft Tissue Sarcomas in Dogs
Synopsis
Histologic grade and surgical margin completeness are the primary prognostic indicators for canine soft tissue sarcomas, with a high mitotic index significantly correlating with reduced survival. While most cases have a favorable prognosis following excision, grade III tumors carry the highest risk of metastasis, necessitating standardized classification and rigorous research to improve clinical outcomes.
Publication date:
01/2011
Pages:
10
Listen
Read
Urologic Oncology
Kristine Elaine Burgess, Carol J. DeRegis
Veterinary Clinics of North America: Small Animal Practice
Kristine Elaine Burgess (et al)
Synopsis
Urologic Oncology
This review addresses the diagnosis and management of rare primary renal tumors and more common transitional cell carcinomas (TCC) in dogs and cats. It highlights the prognostic importance of the mitotic index in renal cell carcinoma and underscores a multimodal treatment strategy for TCC, incorporating advanced diagnostics like BRAF mutation testing, COX-2 inhibitors, and palliative interventional surgery to manage urinary obstructions.
Publication date:
02/2023
Pages:
10
Listen
Read
Optical coherence tomography for surgical margin evaluation of excised canine cutaneous and subcutaneous tumours
Edward Cheng (et al)
Optical coherence tomography for surgical margin evaluation of excised canine cutaneous and subcutaneous tumours
Edward Cheng (et al)
Veterinary and Comparative Oncology
Synopsis
This study demonstrates that optical coherence tomography (OCT) is a highly effective tool for real-time surgical margin evaluation in canine skin tumors, achieving a median sensitivity of 86.7% and specificity of 84.6% in detecting incomplete margins compared to histopathology.
Publication date:
01/06/2022
Pages:
10
Listen
Read
Radical excision with five-centimeter margins for treatment of feline injection-site sarcomas: 91 cases (1998–2002)
Holly A. Phelps (et al)
Holly A. Phelps (et al)
Radical excision with five-centimeter margins for treatment of feline injection-site sarcomas: 91 cases (1998–2002)
Journal of the American Veterinary Medical Association (JAVMA)
Synopsis
This study demonstrates that radical excision with five-centimeter margins significantly improves survival times (901-day median) and reduces local recurrence rates (14%) for feline injection-site sarcomas compared to traditional surgical approaches.
Publication date:
01/07/2011
Pages:
10
Listen
Read
Histologic Grading of Canine Mast Cell Tumor: Is 2 Better Than 3?
S. Sabattini, F. Scarpa, D. Berlato, Bettini
Veterinary Pathology
S. Sabattini (et al)
Histologic Grading of Canine Mast Cell Tumor: Is 2 Better Than 3?
Synopsis
This study demonstrates that the Kiupel 2-tier system is superior to the Patnaik 3-tier system for predicting survival in canine mast cell tumors. By identifying high-risk cases within the ambiguous Patnaik grade II category, the 2-tier system provides better prognostic clarity and more effective guidance for clinical management.
Publication date:
01/2015
Pages:
04
Listen
Read
A systematic review of surgical margins utilized for removal of cutaneous mast cell tumors in dogs
Laura E. Selmic, Audrey Ruple
Laura E. Selmic (et al)
BMC Veterinary Research
A systematic review of surgical margins utilized for removal of cutaneous mast cell tumors in dogs
Synopsis
This systematic review suggests that 2 cm lateral margins and one fascial plane deep provide effective local control for Patnaik grade I and II canine mast cell tumors smaller than 4 cm, resulting in low rates of recurrence and incomplete excision.
Publication date:
2020
Pages:
06
Listen
Read
Efficacy of systemic adjuvant therapies administered to dogs after excision of oral malignant melanomas: 151 cases (2001–2012)
Sarah E. Boston (et al)
Sarah E. Boston (et al)
Efficacy of systemic adjuvant therapies administered to dogs after excision of oral malignant melanomas: 151 cases (2001–2012)
Journal of the American Veterinary Medical Association (JAVMA)
Synopsis
This retrospective study of 151 dogs with oral malignant melanoma found an overall median survival time of 346 days, identifies tumor size, age, and complete surgical excision as key prognostic factors. Crucially, the analysis revealed no significant survival benefit from systemic adjuvant therapies, such as chemotherapy or vaccination, when compared to surgery alone, highlighting the paramount importance of local surgical control.
Publication date:
15/08/2014
Pages:
07
Listen
Read
The effectiveness of using dye models for small tissue biopsies in the surgical pathology laboratory
Predaporn Nonsiri (et al)
Predaporn Nonsiri (et al)
Folia Histochemica et Cytobiologica
The effectiveness of using dye models for small tissue biopsies in the surgical pathology laboratory
Synopsis
This study identifies hematoxylin as an ideal, non-toxic tissue marking dye that significantly improves the visibility of small biopsies (0.2–0.3 cm) during laboratory processing without interfering with pathological diagnosis.
Publication date:
12/06/2023
Pages:
07
Listen
Read
Anaesthesia in Veterinary Oncology: The Effects of Surgery, Volatile and Intravenous Anaesthetics on the Immune System and Tumour Spread
Ana Vidal Pinheiro (et al)
Anaesthesia in Veterinary Oncology: The Effects of Surgery, Volatile and Intravenous Anaesthetics on the Immune System and Tumour Spread
Ana Vidal Pinheiro (et al)
University of Trás-os-Montes e Alto Douro
Synopsis
This review suggests that while surgical stress and volatile anaesthetics suppress immunity and may promote metastasis, propofol displays immunoprotective properties. Consequently, Total Intravenous Anaesthesia (TIVA) combined with regional analgesia is recommended to minimise disease recurrence in veterinary oncology.
Publication date:
01/11/2023
Pages:
17
Listen
Read
Outcome following curative-intent surgery for oral melanoma in dogs: 70 cases (1998–2011)
Joanne L. Tuohy (et al)
Joanne L. Tuohy (et al)
Journal of the American Veterinary Medical Association (JAVMA)
Outcome following curative-intent surgery for oral melanoma in dogs: 70 cases (1998–2011)
Synopsis
This retrospective study of 70 dogs with oral melanoma shows that curative-intent surgery yields a median survival of 723 days. While metastasis and large tumor size reduce survival times, thorough local surgical control remains the cornerstone for achieving long-term outcomes.
Publication date:
11/12/2024
Pages:
08
Listen
Read
MAST CELL TUMORS IN CATS - Clinical update and possible new treatment avenues
Carolyn Henry, Chamisa Herrera
Journal of Feline Medicine and Surgery
Carolyn Henry (et al)
Mast Cell Tumors in Cats - Clinical update and possible new treatment avenues
Synopsis
This review summarizes feline mast cell tumor management, highlighting that while cutaneous lesions typically carry a good prognosis after surgery, visceral forms require thorough staging and may benefit from systemic treatments like tyrosine kinase inhibitors.
Publication date:
2013
Pages:
07
Listen
Read
Scar revision for incompletely or narrowly excised soft tissue sarcomas in dogs
Janet A. Grimes (et al)
The Canadian Veterinary Journal (CVJ)
Janet A. Grimes (et al)
Scar revision for incompletely or narrowly excised soft tissue sarcomas in dogs
Synopsis
This study shows that scar revision for canine soft tissue sarcomas with inadequate margins is highly effective, resulting in a local recurrence rate of only 3.0% and providing durable tumor remission.
Publication date:
01/2023
Pages:
06
Listen
Read