Acute Kidney Injury Defined
Kidney Disease: Improving Global Outcomes Criteria
AKI is defined as any of the following:
- Increase in SCr by > 0.3mg/dl within 48 hours; or
- Increase in SCr to > 1.5 times baseline, which is known or presumed to have occurred within the prior 7 days; or
- Urine volume < 0.5ml/kg/h for 6 hours.
Incorporating elements of Risk, Injury, Loss, End-Stage kidney disease (RIFLE) and AKIN, KDIGO has improved sensitivity and specificity, and it is the internationally accepted standard for defining and staging acute kidney injury (AKI).
Objective
StagingAcute Kidney Injury
By the end of this presentation providers will be able to identify staging criteria for acute kidney injury.
Stage 2
Stage 3
Stage 1
Kidney Disease: Improving Global Outcomes Criteria
> 4.0 mg/dL (353.60 micromol/L) or > 3 times baseline AND< 0.3 mL/kg/hour for > 24 hours or anuria for > 12 hours
> 0.3 mg/dL (26.52 micromol/L) or 1.5–1.9 times baseline AND < 0.5 mL/kg/hour for 6–12 hours
2–2.9 times baseline AND< 0.5 mL/kg/hour for > 12 hours
Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group. (2012). KDIGO clinical practice guideline for acute kidney injury.. Kidney International Supplements, 2(1), 1–138. chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://kdigo.org/wp-content/uploads/2016/10/KDIGO-2012-AKI-Guideline-English.pdf
Wetterstrand, V. J. R., Kallemose, T., Larsen, J. J., Friis-Hansen, L. J., & Brandi, L. (2025). Unpacking KDIGO Guidelines: Prioritizing and Applying Exposures and Susceptibilities for AKI in Clinical Practice. Journal of clinical medicine, 14(8), 2572. https://doi.org/10.3390/jcm14082572
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Staging Acute Kidney Injury
Nicole Kelly
Created on November 2, 2025
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Transcript
Acute Kidney Injury Defined
Kidney Disease: Improving Global Outcomes Criteria
AKI is defined as any of the following:
Incorporating elements of Risk, Injury, Loss, End-Stage kidney disease (RIFLE) and AKIN, KDIGO has improved sensitivity and specificity, and it is the internationally accepted standard for defining and staging acute kidney injury (AKI).
Objective
StagingAcute Kidney Injury
By the end of this presentation providers will be able to identify staging criteria for acute kidney injury.
Stage 2
Stage 3
Stage 1
Kidney Disease: Improving Global Outcomes Criteria
> 4.0 mg/dL (353.60 micromol/L) or > 3 times baseline AND< 0.3 mL/kg/hour for > 24 hours or anuria for > 12 hours
> 0.3 mg/dL (26.52 micromol/L) or 1.5–1.9 times baseline AND < 0.5 mL/kg/hour for 6–12 hours
2–2.9 times baseline AND< 0.5 mL/kg/hour for > 12 hours
Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group. (2012). KDIGO clinical practice guideline for acute kidney injury.. Kidney International Supplements, 2(1), 1–138. chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://kdigo.org/wp-content/uploads/2016/10/KDIGO-2012-AKI-Guideline-English.pdf
Wetterstrand, V. J. R., Kallemose, T., Larsen, J. J., Friis-Hansen, L. J., & Brandi, L. (2025). Unpacking KDIGO Guidelines: Prioritizing and Applying Exposures and Susceptibilities for AKI in Clinical Practice. Journal of clinical medicine, 14(8), 2572. https://doi.org/10.3390/jcm14082572
Got an idea?
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Got an idea?
Use this space to add awesome interactivity. Include text, images, videos, tables, PDFs... even interactive questions! Premium tip: Get information on how your audience interacts with your creation: