KARSMUTATION
VIDEOgame
VIDEOgame
PRESS START
232323
HI-SCORE
MENU
Introduction
characters
missions
© 20XX GENIALLY ESCAPE GAMES
232323
HI-SCORE
INTRODUCTION
Did you know that Genially allows you to share your creation directly, without the need for downloads? Ready for your audience to view it on any device and give it exposure anywhere.
© 20XX GENIALLY ESCAPE GAMES
CHARACTERS
nameplayer
nameplayer
nameplayer
nameplayer
Write a cool subtitle here to provide context
MISSIONS
Complete the missions to obtain the password numbers
4 FROG
3 BARS
2 PUZZLE
1
SHIPS
PASSWORD
LEVEL 1/5
How does the KRAS G12C mutation change the protein’s activity compared to the normal version??
The G12C mutation replaces that glycine with cysteine, which blocks GTP hydrolysis — so the protein stays locked in the “on” position.
Codon 12 sits in the protein’s phosphate-binding loop
KRAS acts like a molecular switch inside cells.
LEVEL 2/5
Why is KRAS so important for regulating cell growth and division??
YAY KARS
When KRAS acts like a molecular switch inside cells. When it’s active, it passes signals from growth factor receptors. These signals tell the cell to grow, divide, or survive.here
Because if they get OUT OF control then you can get health issues
LEVEL 3/5
What makes codon 12 a hotspot for KRAS mutations??
“P-loop,” which helps KRAS hold and hydrolyze GTP. This spot is very sensitive to small changes
WIFI DUH..
glycine
LEVEL 4/5
How do new drugs target KRAS G12C mutations??
BECAUSE ITS MEDICINE
GTP breakdown and keeps KRAS active longer than it should be.
take advantage of the new cysteine’s sulfur group. These drugs form a covalent bond to that cysteine and lock KRAS into an inactive shape, stopping it from sending growth signals.
LEVEL 5/5
Did you LIKE THIS SLIDE SHOW??RIGHT ANSWERS ONLY!!!
MAYBE
OFC, IT'S ANWSOME JUST LIKE YOU!!!
OFC NOT
CONGRATULATIONS!
THE NUMBER OF THIS MISSION IS 1
GAME OVER
CONTINUE?
yes
NO
MISSIONS
Complete the missions to obtain thepassword numbers
4 FROG
3 BARS
2 PUZZLE
1 SHIPS
PASSWORD
LEVEL 1/5
NEXT
HOW DO YOU SPELL ORANGE?
Write
ORANGE
PINK
LEVEL 2/5
NEXT
DO YOU LIKE YOUR JOB?
NO
NO
NO
LEVEL 3/5
NEXT
WHAT IS YOUR AGE?
IDK
65
57
LEVEL 4/5
NEXT
WHAT IS THE BEST SODA?
SPRITE CRANBERRY
PEPSI
CHEERWINE
LEVEL 5/5
NEXT
WHAT IS AN EVEN NUMBER?
BLACK
ME
CONGRATULATIONS!
THE NUMBER OF THIS MISSION IS 2
GAME OVER
CONTINUE?
yes
NO
MISSIONs
Complete the missions to obtain the password numbers
4 FROG
3 BARS
2 PUZZLE
1 SHIPS
PASSWORD
LEVEL 1/5
WHO IS THE BEST SPONGEBOB CHARACTER?
FRED
PATRICK
MR.KRABS
LEVEL 2/5
WHO IS THE BEST HELLO KITTY CHARACTER?
KERROPI
KUROMI
MY MELODY
LEVEL 3/5
WHAT IS THE BEST HOLIDAY?
MY FAVORITE HOLIDAY
VETERIANS DAY
APRIL FOOLS
LEVEL 4/5
DO YOU WATCH NANNY MCPHEE?
NO
NO
YES
LEVEL 5/5
WHAT IS YOUR GENDER
NO
FEMALE
MALE
CONGRATULATIONS!
THE NUMBER OF THIS MISSION IS 3
GAME OVER
CONTINUE?
yes
NO
missions
Complete the missions to obtain thenumbers of the password
4 FROG
3 BARS
2 PUZZLE
1 SHIPS
PASSWORD
LEVEL 1/3
DO YOU LIKE FROGS?
NO
MAYBE
YES
LEVEL 2/3
DO YOU LIKE BLUEY ?
NO
ITS THE BEST SHOW
NO
LEVEL 3/3
WHATS THE BEST COLOR?
WHITE
GRAY
Write the correct answer here
CONGRATULATIONS!
THE NUMBER OF THIS MISSION IS 4
GAME OVER
CONTINUE?
yes
NO
missions
Complete the missions to obtain thepassword numbers
4 FROG
3 BARS
2 PUZZLE
1 SHIPS
PASSWORD
Introduce la contraseña correcta 👾
Números conseguidos de las misiones
Are you sure you want to exit?
You will lose all the progress
NO
yes
Are you sure you want to exit?
You will lose all the progress
NO
yes
Are you sure you want to exit?
You will lose all the progress
NO
yes
Are you sure you want to exit?
You will lose all the progress
NO
yes
MIsSIONSHIPS
I am a cool subtitle, perfect for providing more context about the topic you're going to discuss
CONTINUE
nameplayer
I am a cool subtitle, ideal for providing more context about the topic you are going to address
Are you sure you want to exit?
You will lose all the progress
NO
yes
nameplayer
I'm a cool subtitle, perfect for providing more context about the topic you are going to address
MISSIONpuzzle
I am a cool subtitle, ideal for providing more context about the topic you are going to talk about
CONTINUE
Missionbars
I am a cool subtitle, perfect for providing more context about the topic you are going to discuss
CONTINUE
Are you sure you want to exit?
You will lose all the progress
NO
yes
Are you sure you want to exit?
You will lose all the progress
NO
yes
Are you sure you want to exit?
You will lose all the progress
NO
yes
Are you sure you want to exit?
You will lose all the progress
NO
yes
Are you sure you want to exit?
You will lose all the progress
NO
yes
Are you sure you want to exit?
You will lose all the progress
NO
yes
Are you sure you want to exit?
You will lose all the progress
NO
yes
Are you sure you want to exit?
You will lose all the progress
NO
yes
MISSIONfrog
I am a cool subtitle, perfect to provide more context about the topic you are going to discuss
CONTINUE
Are you sure you want to exit?
You will lose all the progress
NO
yes
nameplayer
I am a cool subtitle, ideal to provide more context about the topic you are going to address
nameplayer
I am a cool subtitle, perfect to provide more context about the topic you are going to address
Are you sure you want to exit?
You will lose all the progress
NO
yes
Are you sure you want to exit?
You will lose all the progress
NO
yes
Are you sure you want to exit?
You will lose all the progress
NO
yes
Are you sure you want to exit?
You will lose all the progress
NO
yes
VIDEOgame
Jaíde
Created on October 28, 2025
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Transcript
KARSMUTATION
VIDEOgame
VIDEOgame
PRESS START
232323
HI-SCORE
MENU
Introduction
characters
missions
© 20XX GENIALLY ESCAPE GAMES
232323
HI-SCORE
INTRODUCTION
Did you know that Genially allows you to share your creation directly, without the need for downloads? Ready for your audience to view it on any device and give it exposure anywhere.
© 20XX GENIALLY ESCAPE GAMES
CHARACTERS
nameplayer
nameplayer
nameplayer
nameplayer
Write a cool subtitle here to provide context
MISSIONS
Complete the missions to obtain the password numbers
4 FROG
3 BARS
2 PUZZLE
1 SHIPS
PASSWORD
LEVEL 1/5
How does the KRAS G12C mutation change the protein’s activity compared to the normal version??
The G12C mutation replaces that glycine with cysteine, which blocks GTP hydrolysis — so the protein stays locked in the “on” position.
Codon 12 sits in the protein’s phosphate-binding loop
KRAS acts like a molecular switch inside cells.
LEVEL 2/5
Why is KRAS so important for regulating cell growth and division??
YAY KARS
When KRAS acts like a molecular switch inside cells. When it’s active, it passes signals from growth factor receptors. These signals tell the cell to grow, divide, or survive.here
Because if they get OUT OF control then you can get health issues
LEVEL 3/5
What makes codon 12 a hotspot for KRAS mutations??
“P-loop,” which helps KRAS hold and hydrolyze GTP. This spot is very sensitive to small changes
WIFI DUH..
glycine
LEVEL 4/5
How do new drugs target KRAS G12C mutations??
BECAUSE ITS MEDICINE
GTP breakdown and keeps KRAS active longer than it should be.
take advantage of the new cysteine’s sulfur group. These drugs form a covalent bond to that cysteine and lock KRAS into an inactive shape, stopping it from sending growth signals.
LEVEL 5/5
Did you LIKE THIS SLIDE SHOW??RIGHT ANSWERS ONLY!!!
MAYBE
OFC, IT'S ANWSOME JUST LIKE YOU!!!
OFC NOT
CONGRATULATIONS!
THE NUMBER OF THIS MISSION IS 1
GAME OVER
CONTINUE?
yes
NO
MISSIONS
Complete the missions to obtain thepassword numbers
4 FROG
3 BARS
2 PUZZLE
1 SHIPS
PASSWORD
LEVEL 1/5
NEXT
HOW DO YOU SPELL ORANGE?
Write
ORANGE
PINK
LEVEL 2/5
NEXT
DO YOU LIKE YOUR JOB?
NO
NO
NO
LEVEL 3/5
NEXT
WHAT IS YOUR AGE?
IDK
65
57
LEVEL 4/5
NEXT
WHAT IS THE BEST SODA?
SPRITE CRANBERRY
PEPSI
CHEERWINE
LEVEL 5/5
NEXT
WHAT IS AN EVEN NUMBER?
BLACK
ME
CONGRATULATIONS!
THE NUMBER OF THIS MISSION IS 2
GAME OVER
CONTINUE?
yes
NO
MISSIONs
Complete the missions to obtain the password numbers
4 FROG
3 BARS
2 PUZZLE
1 SHIPS
PASSWORD
LEVEL 1/5
WHO IS THE BEST SPONGEBOB CHARACTER?
FRED
PATRICK
MR.KRABS
LEVEL 2/5
WHO IS THE BEST HELLO KITTY CHARACTER?
KERROPI
KUROMI
MY MELODY
LEVEL 3/5
WHAT IS THE BEST HOLIDAY?
MY FAVORITE HOLIDAY
VETERIANS DAY
APRIL FOOLS
LEVEL 4/5
DO YOU WATCH NANNY MCPHEE?
NO
NO
YES
LEVEL 5/5
WHAT IS YOUR GENDER
NO
FEMALE
MALE
CONGRATULATIONS!
THE NUMBER OF THIS MISSION IS 3
GAME OVER
CONTINUE?
yes
NO
missions
Complete the missions to obtain thenumbers of the password
4 FROG
3 BARS
2 PUZZLE
1 SHIPS
PASSWORD
LEVEL 1/3
DO YOU LIKE FROGS?
NO
MAYBE
YES
LEVEL 2/3
DO YOU LIKE BLUEY ?
NO
ITS THE BEST SHOW
NO
LEVEL 3/3
WHATS THE BEST COLOR?
WHITE
GRAY
Write the correct answer here
CONGRATULATIONS!
THE NUMBER OF THIS MISSION IS 4
GAME OVER
CONTINUE?
yes
NO
missions
Complete the missions to obtain thepassword numbers
4 FROG
3 BARS
2 PUZZLE
1 SHIPS
PASSWORD
Introduce la contraseña correcta 👾
Números conseguidos de las misiones
Are you sure you want to exit?
You will lose all the progress
NO
yes
Are you sure you want to exit?
You will lose all the progress
NO
yes
Are you sure you want to exit?
You will lose all the progress
NO
yes
Are you sure you want to exit?
You will lose all the progress
NO
yes
MIsSIONSHIPS
I am a cool subtitle, perfect for providing more context about the topic you're going to discuss
CONTINUE
nameplayer
I am a cool subtitle, ideal for providing more context about the topic you are going to address
Are you sure you want to exit?
You will lose all the progress
NO
yes
nameplayer
I'm a cool subtitle, perfect for providing more context about the topic you are going to address
MISSIONpuzzle
I am a cool subtitle, ideal for providing more context about the topic you are going to talk about
CONTINUE
Missionbars
I am a cool subtitle, perfect for providing more context about the topic you are going to discuss
CONTINUE
Are you sure you want to exit?
You will lose all the progress
NO
yes
Are you sure you want to exit?
You will lose all the progress
NO
yes
Are you sure you want to exit?
You will lose all the progress
NO
yes
Are you sure you want to exit?
You will lose all the progress
NO
yes
Are you sure you want to exit?
You will lose all the progress
NO
yes
Are you sure you want to exit?
You will lose all the progress
NO
yes
Are you sure you want to exit?
You will lose all the progress
NO
yes
Are you sure you want to exit?
You will lose all the progress
NO
yes
MISSIONfrog
I am a cool subtitle, perfect to provide more context about the topic you are going to discuss
CONTINUE
Are you sure you want to exit?
You will lose all the progress
NO
yes
nameplayer
I am a cool subtitle, ideal to provide more context about the topic you are going to address
nameplayer
I am a cool subtitle, perfect to provide more context about the topic you are going to address
Are you sure you want to exit?
You will lose all the progress
NO
yes
Are you sure you want to exit?
You will lose all the progress
NO
yes
Are you sure you want to exit?
You will lose all the progress
NO
yes
Are you sure you want to exit?
You will lose all the progress
NO
yes