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Antibiotic Apocalypse- NURSING EDITION

Ricardo Arbulu

Created on October 23, 2025

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Transcript

antibiotic apocalypse

Nursing edition

Start

Dr.HOPE

This is Dr. Hope, reaching you from the year 3000 AD. Humanity has been nearly wiped off the face of the earth by multi-drug-resistant bacteria… I found this ancient computer from UPMC Mercy... The protocols it contains seem to hold the key to using antibiotics wisely and save our planet!

Dr.HOPE

But I need your help! I need you to crack into InfoNET to verify these protocols are not corrupted. We don’t have much time until we loose connection… Let’s go!

I retrieved the document "Betalactam Allergy Evaluation" but the text is corrupted. Find it in Infonet and complete this excerpt from the Patient Interview Questions. Make sure to pull the protocol, don't guess!

Dr.HOPE

If only we had asked people about their penicillin allergy! We would have avoided unnecessary broad-spectrum antibiotics a lot more! 90% of people who claim that allergy in the US can safely tolerate penicillin-type antibiotics, so this is a critical intervention. You guys had such a nice protocol to know exactly what to ask!.. Let's move on...

I found this email from one Mercy nurse to another explaining this, back in your day: “Since so many patients claim a penicillin allergy inaccurately, many are deemed such a low risk that the standard of care is to “challenge” them with 10% of the normal dose of antibiotic, and if they tolerate, with the full dose. It is an order set for physicians, and it can be carried out safely in the med/surg units. The pharmacists are very supportive throughout this.”

Switching gears, it looks like you guys had a great strategy to reduce unnecessary vancomycin at UPMC back in your day! Here is what I understand: Collecting MRSA swabs in a prompt fashion was obviously quite impactful in reducing unnecessary vancomycin, right? .

  • Vancomycin is most often given for MRSA.
  • In patients with pneumonia, a negative nasal MRSA screen can quickly exclude MRSA as the culprit, and lead to discontinuation of vancomycin.

Retrieve the document called “Biofire Blood Culture Rapid Identification Clinical Pathway” from InfoNET. Now use it to know what to do: A patient grows Citrobacter spp. in blood, and the PCR identifies the resistance marker “CTX-M". Find the antibiotic that is recommended.

I am vanishing!! ... My timeline is being erased!!! ... so the the antibiotic apocalypse must have been prevented in my past... which is your future... perhaps due to the protocols you just learned...

THE END

Retrieve the document called “Biofire Blood Culture Rapid Identification Clinical Pathway” from InfoNET. Now use it to know what to do: A patient grows Citrobacter spp. in blood, and the PCR identifies the resistance marker “CTX-M". Find the antibiotic that is recommended.

Ilum even tells you the percentage of isolates susceptible per organism at Mercy! If we had used that information in all hospitals, this apocalypse would have never happened.

antibiotic steward

Tonight, a sealed envelope soaked by the rain was left under my door. Inside, there was a message, but something about it didn't add up…

Vera

Krohn... After so many years? I don't even remember the last time I saw him… Does that laboratory still exist? Well, it's important that you remember the computer password: REBOOT PROTOCOL

Mission 1

underground lab

Vera

There is no one left here. Only emptiness… and echoes. But in this place, there are still secrets in the air. And it seems that someone was expecting me...

dr.Krohn

Your responses have unlocked an important discovery. Go see Quincy. He has the last piece of the protocol.

Mission 2

The Clone Club

Vera

Krohn dead?? When did it happen? And now he sends me to find that obsolete cyborg, Quincy… I don’t know what answers he will give me, but there’s no turning back now.

QUINCY

vera

QUINCY

- Now you are here.

vera

- Were you waiting for me?

QUINCY

- Krohn predicted this moment. A long time ago.

vera

- What happened to him? What aren’t you saying?

QUINCY

- There is no time for nostalgia. There is no time… Now I need to check your abilities...

QUINCY

vera

QUINCY

- Krohn knew you would evolve. He programmed the message to be sent decades ago, hoping you would develop consciousness.

You are a cyborg, Vera. Like me. But I was limited.

You let yourself grow, evolve, become more human. And if you reached this point, I had to restart you.

The time has come. I was created for this… I feel no guilt.

The protocol requires it. You must be restarted.

vera

- Was my whole life... an experiment?

Mission 3

data network

Vera

I don't know if I'm AI or something else… but these memories belong to me. They are my life. I need to organize them before they are erased. Before I disappear.

QUiNCY

vera

quincy

- Now you know. Khron had reasons to fear this moment would come. You are designed to question everything. And that makes you dangerous.

vera

- I am not just lines of code. I feel.I doubt. I choose.

Isn’t that what makes humans human?

quincy

- Or... what destroys them.

Decide Vera's fate

the final choice

Rebel against the protocol

ASSUME your limitations as an AI

END

"Freedom is an error I cannot afford."

Vera assumes it is an AI. It follows the protocol. It restarts.

END

"If feeling is dangerous… then I choose danger."

Vera rebels. She escapes and begins a new life in the shadows.

Text

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