Muscle diseases project
John Huff
iBM
Inclusion body myositis (IBM) is a degenerative muscle disease that causes gradual and painless weakening of your muscles. It occurs mostly in men who are about 50+ years of age.
the impact
IIBM mostly affects the bones of the hands and wrists and may affect the bone of the front of the thigh.
Causes
In most cases, the cause of inclusion body myositis (IBM) is unclear. Some viral infections or exposure to certain drugs have been reported to trigger IBM. In general, researchers believe that factors related to the immune system, genetics, aging and the environment all play a role in IBM development.
Symptoms
Inclusion body myositis (IBM) usually begins with the gradual onset of slowly progressive weakness in skeletal muscles (muscles that connect to bones and allow movement). Initially, people with IBM may experience some proximal (close to the body center) leg weakness, which can cause difficulty getting up from a chair or frequent falls. Some people may have trouble gripping with their hands, for instance when opening a jar. It is common for people to assume that these initial symptoms are a result of aging.
IBM symptoms can vary greatly in different people. Most people with IBM experience weakness in the distal (far from the body center) flexor muscles of the wrists and fingers, and the muscles of the front of the thigh (e.g., hip flexors, knee extensors). Asymmetric (on one side of the body) and distal muscle weakness are more likely to appear in IBM than in other IIMs. About half of people with IBM experience difficulty swallowing (dysphagia).
treatment
There’s no effective course of treatment for inclusion body myositis. Unlike other inflammatory and autoimmune conditions, it doesn’t respond to corticosteroids or immunosuppressant drugs. But physical therapy and regular exercise are crucial to preserving your muscle strength as much as possible.
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Peter Frampton
'Your content is liked, but it engages much more if it is interactive'- Genially
thanks
Muscle diseases project
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Transcript
Muscle diseases project
John Huff
iBM
Inclusion body myositis (IBM) is a degenerative muscle disease that causes gradual and painless weakening of your muscles. It occurs mostly in men who are about 50+ years of age.
the impact
IIBM mostly affects the bones of the hands and wrists and may affect the bone of the front of the thigh.
Causes
In most cases, the cause of inclusion body myositis (IBM) is unclear. Some viral infections or exposure to certain drugs have been reported to trigger IBM. In general, researchers believe that factors related to the immune system, genetics, aging and the environment all play a role in IBM development.
Symptoms
Inclusion body myositis (IBM) usually begins with the gradual onset of slowly progressive weakness in skeletal muscles (muscles that connect to bones and allow movement). Initially, people with IBM may experience some proximal (close to the body center) leg weakness, which can cause difficulty getting up from a chair or frequent falls. Some people may have trouble gripping with their hands, for instance when opening a jar. It is common for people to assume that these initial symptoms are a result of aging. IBM symptoms can vary greatly in different people. Most people with IBM experience weakness in the distal (far from the body center) flexor muscles of the wrists and fingers, and the muscles of the front of the thigh (e.g., hip flexors, knee extensors). Asymmetric (on one side of the body) and distal muscle weakness are more likely to appear in IBM than in other IIMs. About half of people with IBM experience difficulty swallowing (dysphagia).
treatment
There’s no effective course of treatment for inclusion body myositis. Unlike other inflammatory and autoimmune conditions, it doesn’t respond to corticosteroids or immunosuppressant drugs. But physical therapy and regular exercise are crucial to preserving your muscle strength as much as possible.
famous person
Peter Frampton
'Your content is liked, but it engages much more if it is interactive'- Genially
thanks