Want to create interactive content? It’s easy in Genially!
Help the cell to signal growth
BENJAMIN MORSE
Created on July 10, 2025
Start designing with a free template
Discover more than 1500 professional designs like these:
View
Artificial Intelligence in Corporate Environments
View
Internal Guidelines for Artificial Intelligence Use
View
Interactive Onboarding Guide
View
Word Search
View
Sorting Cards
View
Word Search: Corporate Culture
View
Corporate Escape Room: Operation Christmas
Transcript
Help the cell to signal growth
Start
Goal/Instructions
Before you can unlock the 4 "posts" you need to pass the "interview" and show your knowledge of the basics for the cell to hire you
Interview Request
Prepare for interview
Types of Cell Signaling
Parts of a signaling pathways
Signal amplification
Responses to signaling pathways
Types of Signaling pathways
Go to Pathway 1: (RTK)
Pathway 1: RTK
Click to Unlock
Answer:
Resources
Parts of RTK
Video
Reading
Process of RTKs
Use or RTKs in Cross Talk
Reveal RTK Key
Social Media
Pathway 2: GCPR
Click to Unlock
Answer:
Resources
Parts of GPCR
Video
Reading
Processes of a GCPR
Use or GPCR in Cross Talk
Reveal GCPR Key
Insta
Pathway 3: Intracellular Receptor
Resources
Click to Unlock
Answer:
Video
Reading
Parts of intracellular receptors
Intracellular Receptor Targets
Reveal GCPR Key
Addiction
Pathway 4: Ion Channel
Resources
Click to Unlock
Video
Reading
Answer:
Parts of Ion Channel
Processes of a Ion Channel
Uses of an Ion channel
Reveal GCPR Key
Meme
Grow Followers
Click me!
Click me!
Congratulations
Your cell divided!
...
Title 1
...
...
...
Subtitle
...
...
What causes the subunits to come together
non-spontaneous interaction
Binding of the ligand
Binding of the substrate
Enzyme mediated interaction
Which molecule is required for RTK kinase activity?
ATP
NAD+
NADH
ADP
What is autophosphrylation in the context of RTKS
It is when the subunits on the intercellular side of RTK add phosphates each other's serine residues
It is when the subunits on the intercellular side of RTK add phosphates each other's tyrosine residues
It is when the subunits on the intercellular side of RTK add phosphates each other's tryptophan residues
It is when the subunits on the intercellular side of RTK add phosphates each other's threonine residues
You are the social media manager for the cell. Your mission is to get all the signal pathways "messages/posts" to reach their target audiance so the cell can "Grow Followers". Answer basic questions in the "interview section" to get hired and unlock the 4 pathways. Complete each pathway to unlock the "Grow Followers" option so the cell can divide.
Subtitle
...
Title 1
...
...
...
...
...
...
Click the X
I am looking for someone who can help me post my cell signals as I am trying to grow my social media. It is important I get good reception and prompt responses from my followers, but block those spam accounts at all costs! Can you help?
Sure, i'll make you INSTA famous!
EW! you arE Gross!
types of ion channels
One- Monomer
Two- Dimer
Three- Trimer
Four- Tetramer
How is the central pore selective for specific ions
Real Time Kinetics
Receptor Tryptophan Kinase
Receptor Tyrosine Kinase
Reciever Tyrosine Kinase
why is gating necessary for some ion channels
Kinase domain
Transmembrane domain
SH2 Domain
Ligand-binding domain
Where is a hormone receptor found?
in the mitochondria
in the membrane like all the others
in the cytosol
in the nucleous
How does the hormone reach the receptor?
binds at the membrane
the receptor moves to the ligand
the hormone difusses into the cytosol
gets transported via a transport protein
why can a hormone diffuse through the membrane while other ligands cannot
It is charged
it is large and powerful
it is small and polar
it is small and nonpolar
The image to the left is an example of what?
Cross talk
a linear pathway
U serious brah?
Talk back
The ? on the image to the right is an example of
Secondary signaling molecule
Scafolding protein
Cross talk protein
Kinase
What causes the subunits to come together
non-spontaneous interaction
Binding of the ligand
Binding of the substrate
Enzyme mediated interaction
Which molecule is required for RTK kinase activity?
ATP
NAD+
NADH
ADP
What is autophosphrylation in the context of RTKS
It is when the subunits on the intercellular side of RTK add phosphates each other's serine residues
It is when the subunits on the intercellular side of RTK add phosphates each other's tyrosine residues
It is when the subunits on the intercellular side of RTK add phosphates each other's tryptophan residues
It is when the subunits on the intercellular side of RTK add phosphates each other's threonine residues
What is the target for the receptor complex
mitochondria
Gene
nucleous
transcript
Is there a signal amplification step?
no
yes
Why isn't there a signal amplification step?
There are only 2 copies of each gene that can be targeted
Lies! there is an amplification step
Because the incomming signal is stronger than others
What is the result of the receptor being targeted to the gene?
transcription is turned on for target genes
The cell recieves the nuclear signal and "nukes" itself (apoptosis).
gene translation is turned on
the mitochondria is activated
which is not part of a GCPR system
GTP protein
ATP
Receptor
Effector
What are some examples of an effector
adenylate cyclase
phospholipase
all of the above
ion channels
which is not a subunit of the G protein
alpha
beta
gamma
delta
The image to the left is an example of what?
Cross talk
a linear pathway
U serious brah?
Talk back
The ? on the image to the right is an example of
Secondary signaling molecule
Scafolding protein
Cross talk protein
Kinase
How many subunits make up an active RTK?
One- Monomer
Two- Dimer
Three- Trimer
Four- Tetramer
What does RTK stand for?
Real Time Kinetics
Receptor Tryptophan Kinase
Receptor Tyrosine Kinase
Reciever Tyrosine Kinase
Which domain is typically found on the extracellular portion of RTKs?
Kinase domain
Transmembrane domain
SH2 Domain
Ligand-binding domain
What causes the subunits to come together
non-spontaneous interaction
Binding of the ligand
Binding of the substrate
Enzyme mediated interaction
Which molecule is required for RTK kinase activity?
ATP
NAD+
NADH
ADP
What is autophosphrylation in the context of RTKS
It is when the subunits on the intercellular side of RTK add phosphates each other's serine residues
It is when the subunits on the intercellular side of RTK add phosphates each other's tyrosine residues
It is when the subunits on the intercellular side of RTK add phosphates each other's tryptophan residues
It is when the subunits on the intercellular side of RTK add phosphates each other's threonine residues
...
Subtitle
Title 1
...
...
...
...
...
synaptic terminals
Cross talk
a linear pathway
U serious brah?
Talk back
relay of electrical signals down axons
pressure gated cahnnels for perciving touch and sound
intracellular signaling with Ca+2 channels
Secondary signaling molecule
Scafolding protein
Cross talk protein
Kinase
...
Title 1
...
...
...
...
Subtitle
...
ANSWER THESE QUESTIONS: What is an embeded protein in a membrane that allows for cell signaling called?
Cell Receptor
Enzyme
Transport protein
Signal carrier
What is the small molecule that binds to a receptor called?
Substrate
Ligand
Reciever
Left hand
Back to start
Endocrine
Paracrine
Direct
Which type of cell signaling utilizes hormones?
Direct
Endocrine
Paracrine
Direct Cells make physical contact
Paracrine
Endocrine
ligands diffuses a short distance to reach target cell
Long distance signaling using hormones and the blood stream
Answer question here
Notice how one ligand ends in the signal repeated many times.
Secondary Messengers
Phosphorylation Cascade
a series of chemical reactions in a cell where a protein kinase enzyme adds phosphate groups to other specific proteins, leading to a series of protein modifications that amplify and transmit the signal.
Purpose of signal amplification
Signal amplification occurs when a signaling molecule binds to its receptor, leading to a larger cellular response through the activation of multiple molecules.
Which molecules help to relay and amplify signals from receptors on the cell surface to target molecules within the cell?
--> Uses Kinases (enzyme) --> Requires ATP to add phosphate group (phosphorylate ) different proteins --> Leads to conformational change in intermediate proteins
Click on picture
cyclic AMP and Ca +2 allows the "posts" to be spread faster
Click on picture
Resources:
Khan Academy
Textbook reading
Ameoba sisters
Responses to signaling pathways