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Expanded Hemodialysis & Medium Cut-off Dialyzers

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Created on March 20, 2025

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Expanded Hemodialysis & Medium Cut-off Dialyzers

WHAT YOU NEED TO KNOW

What is a Dialyzer?

A dialyzer is the "artificial kidney" or "filter" used for hemodialysis treatments.

+ How it Works

What is Expanded Hemodialysis (HDx)?

HDx uses a new type of dialyzer during hemodialysis called a medium cut-off (MCO) dialyzer. It removes a wider or "expanded" range of waste products called uremic toxins that build up in the body due to kidney failure.

+ Learn More

Types of Dialyzers

Different types of dialyzers can filter out different sizes of toxins.

What to Ask Your Dialysis Team

  • What type of dialyzer is used for my dialysis treatment?
  • How does my dialysis team decide which type of dialyzer is best for me?
  • If I have symptoms like itching, restless legs, poor sleep, and/or fatigue, will you try another type of dialyzer?
  • Will my doctor consider trying an MCO dialyzer which may improve how I feel?
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This content is provided for informational purposes only and is not intended as medical advice or as a substitute for the medical advice of a healthcare professional.

How Does HDx Work?

HDx removes large waste products called middle molecules that build up in the body and cause uremic symptoms (itching, feeling very tired, muscle cramps, nausea, vomiting, loss of appetite, weight loss, restless legs, bone pain, shortness of breath). Removing these waste products with HDx has been linked to a person feeling better and have some better treatment results. Your doctor may be able to change your current dialyzer to an MCO dialyzer for HDx. The same machine used in your dialysis unit can be used for HDx. The staff does not need to do anything extra to use an MCO dialyzer for HDx.

How it Works

In hemodialysis, blood is taken from the body, cleaned in the dialyzer to remove waste and extra fluid, and then put back into the body. There are different types of dialyzers, such as low flux, high flux, and the new medium cut-off (MCO) dialyzer.