Aspirin Medication Teaching

Aspirin

Purpose

Brand Name: Aspro Clear®, Disprin® Aspalgin®, Codral Cold & Flu Original®

Aspirin is a pharmaceutical drug used to reduce pain or inflammation. Asprin's uses: - relief of mild to moderate pain and fever -relief of inflammatory symptoms (swelling) - body temperature reduction - reducing the ability of platelets to to stick together and to damaged blood vessels, which prevents blood clots from formingSome people are prescribed asprine at low doses over a long time to help reduce the risk of heart attack and stoke, known as 'aspirin therapy'.

Aspirin

Prevents Blood Clots

Aspirin prevents the production of thromboxane A2, which is essential for platelet aggregation. A single dose of aspirin prevents platelet aggregation for the lifespan of the platelet, which is about 5 to 7 days

Aspirin also prevents the production of PGs that protect the stomach mucosa from damage by hydrochloric acid.

Aspirin prevents the production of PGs that maintain kidney function.

Maintains Kidney Function

Prevents Stomach Damage

By inhibiting COX, aspirin reduces inflammation, pain, fever, and swelling

Reduces Inflammation

Aspirin prevents the production of PGs by inhibiting the activity of COX.

Inhibits COX

How Does It Work?

You should not use aspirin if you have a bleeding disorder such as hemophilia, a recent history of stomach or intestinal bleeding. If you are allergic to an NSAID (non-steroidal anti-inflammatory drug) such as Advil, Motrin, Aleve, Orudis, Indocin, Lodine, Voltaren, Toradol, Mobic, Relafen, Feldene, and others'.

Who Should Not Take This Medication?

Intracerebral Hemorrhage Aspirin increases the risk of this. A dangerous condition that occurs when a blood vessel in the brain bursts and bleeds into the brain tissue

Reye's Syndrome Rare but serious condition that cause confusion, swelling in the brain, and liver damage

Hypersensitivity The immune system has an exaggerated response to a drug or substance, ending in damaging instead or protecting

Adverse Effects

Long-term effects Regular use of aspirin may eventually cause:

• anaemia (low red blood cell count)
• easy bruising and abnormal bleeding
• inflamed stomach lining, stomach bleeding, and peptic ulcers
• vomiting blood that look like coffee grounds
• bowel motions that look like black tar
• in some rare cases swelling of the face, lips, tongue or around the eyes
• reduced kidney and liver function

• nausea or vomiting
• trouble breathing (rapid or shallow breath)
• ringing ears or unable to hear

• fever or sweating
• confusion
• seizures
• coma

Overdose If you take a large amount of aspirin, you could overdose. Overdose symptoms usually occur within 6-12 hours of taking aspirin.Asprin can cause death. Call an ambulance straight away by dialling triple zero (000) if you, or someone else, has taken too much aspirin or is experiencing any of the following symptoms:

Side effects The most common side effects of aspirin are:

• dizziness
• ringing in the ears
• blurred vision
• drowsiness and fatigue
• thirst and sweating
• swollen ankles
• abdominal discomfort or bloating
• nausea
• heartburn
• diarrhoea
• constipation

Use of any drug can have risks. It’s important to be careful when taking any type of drug.

Aspirin affects everyone differently, based on: size, weight and health, whether the person is used to taking it, whether other drugs are taken around the same time, the amount taken, andthe strength of the drug (varies by brand).

Potential/Common Side Affects

Therapeutic drug levels for aspirin are 150 to 300 mcg/mL (salicylate). Toxic Levels: Greater than 300 mcg/mL Timing: 1 to 3 hours after the dose Time to Steady State: 5 to 7 days

Aspirin levels do not need to be monitored in most cases. For certain diseases, serum creatinine at baseline, along with serum drug levels, if patients have adult or juvenile rheumatoid arthritis, Kawasaki disease, or arthritis/pleurisy.

Due to delayed absorption of certain preparations, levels should be checked 4 hours after consumption and every subsequent 2 hours until maximum levels are reached.

(labs, vitals, signs, etc..)

Monitoring

https://adf.org.au/drug-facts/aspirin/ https://www.ncbi.nlm.nih.gov/books/NBK519032/ https://www.rxlist.com/aspirin/generic-drug.htm

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