Pair win Nobel prize in chemistry for work on organic catalysts
The importants notions :
something that makes a chemical reaction happen more quickly without itself being changed
a catalyst :
a mirror image :
David Macmillan
Benjamin List
Why is this Research Important ?
development of numerous organic catalysts
environmentally friendly
increases the efficiency of compound production
inexpensive
produces specific mirror images of molecules
Advances in the Pharmaceutical Industry
asymmetric organocatalysis
the thalidomide scandal of the 1950s and 1960s
undesirable mirror image of the product
isolates rare substances
makes it possible to manufacture molecules --> large quantities
produces paroxetine and oseltamivir
CONCLUSION
the discovery of a new class of catalysts
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List’s Study
an asymmetric catalysis
recalled research from the 1970s
the amino acids
an organic chemistry reaction : aldolization
MacMillan’s Study
catalyze a carbon-carbon bond formation
asymmetric metal catalysis
only one mirror image of the product
this method was impractical for industry
an organic molecule -->an iminium ion
developing organic molecules