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Copy of 2.2.4 Clues in the Chromosomes.pptx

Corynn McAtee

Created on October 28, 2024

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2.2.4 Clues in the Chromosomes

Concerns about short height

  • previously discussed nutrition recommendations with family
  • Height goal: 94 cm

5 year old female In the clinic with her father, Julio

RELEVANT HISTORY

MEET YOUR NEXT PATIENT! RILEY HERNANDEZ

A NOT-SO-WELL VISIT

DID SHE REACH HER HEIGHT GOAL?

You have serious concerns about Riley not meeting her height goals. You must consider a variety of possible causes. Brainstorm with a partner to generate a list of ideas about what could be causing this delay in growth for Riley. When finished, share your list with the class and discuss.

Growth Concerns

STEPS TOWARDS DIAGNOSIS

RILEY'S RESULTS:

EXAMPLES OF HORMONES THAT REGULATE GROWTH

WHAT SYSTEM CONTROLS HORMONES?

WHAT SECRETES HORMONES?

WHAT ARE HORMONES?

POSSIBLE HORMONE IMBALANCE?

What are chromosomes? What is a chromosomal disorder? How is that different from a single gene disorder?

CHROMOSOMAL DISORDERS

  • what is a cytogeneticist?
  • what was Barbara McClintock's contribution to genetics?
  • what is a "jumping gene" (transposable element)?

Watch the Chromosome spread module videos together 2.2.4 > chromosome spreads

WHAT IS A CHROMOSOME SPREAD?

READ THE HISTORICAL HIGHLIGHT

IT'S YOUR TURN!

ETHICS DISCUSSION:

  • TREATING HUMAN CELLS WITH RESPECT
  • HENRIETTA LACKS & THE CONTRIBUTION OF HELA CELLS

YOU WILL USE HUMAN TUMOR CELLS TO CREATE A CHROMOSOME SPREAD THEN YOU WILL STAIN THE CHROMOSOMES THEN, VIEW UNDER A MICROSCOPE

TO THE LAB!

Is this individual male or female?

KARYOTYPING

How many chromosomes does a typical human somatic cell have? How many pairs? How many are autosomes? How many are sex chromosomes?