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Lauralie Svabek

Created on October 26, 2024

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Transcript

Antidepressant treatment-related brain activity changes in remitted major depressive disorder

Psychiatry Research: NeuroimagingVolume 330, April 2023, 111601

Regions of the brain explored

Left Inferior Temporal Gyrus (A), Right Cerebellum Crus (B), Left Lingual Gyrus (C), Left Dorsal Medial Prefrontal Gyrus (D), and Left Dorsal Lateral Prefrontal Gyrus (E)

Comparaison between baseline and follow-up

Those increased functional connectivity...

Between DLPFC and Cerebellum

Improve cognitive process

Enhance working memory

Between Insula and ITG

Help in decision-making

Improve emotional processes

Limitations : variability in prescribed medications, small sample size -> Need further research

Abnormal functional connectivity in several networks can be regulated by antidepressant treatment DMPFC = potential neural target.