Anglais

Psychiatry Research: NeuroimagingVolume 330, April 2023, 111601

Antidepressant treatment-related brain activity changes in remitted major depressive disorder

Left Inferior Temporal Gyrus (A), Right Cerebellum Crus (B), Left Lingual Gyrus (C), Left Dorsal Medial Prefrontal Gyrus (D), and Left Dorsal Lateral Prefrontal Gyrus (E)

Regions of the brain explored

Comparaison between baseline and follow-up

Improve emotional processes

Improve cognitive process

Those increased functional connectivity...

Enhance working memory

Help in decision-making

Between DLPFC and Cerebellum

Between Insula and ITG

Abnormal functional connectivity in several networks can be regulated by antidepressant treatment DMPFC = potential neural target.

Limitations : variability in prescribed medications, small sample size-> Need further research