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2.2.1+Bothersome+Bumps.pptx.pptx
Corynn McAtee
Created on October 23, 2024
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Transcript
2.2.1 Bothersome Bumps
PBS
Meet Kai Rossi!
- 7 year old
- Male
- Unexplained bumps under skin on legs
- Ordered an MRI
It's Your Turn! Preliminary Possibilities
Go to PLTW 2.2.1 > Cellular Concerns
- Terminology - define differential diagnosis & answer reflection question (under Preliminary Possibilities)
- Step 1 – review Kai's patient portal
- Record MRI results and any other concerning info
- Step 2 – work with a partner to research to generate a differential diagnosis (create a list of at least 3 possibilities).
Behind the Biopsy
To understand what is causing the solid mass tumors, we must have a full understanding of human cells
- Humans are made of _______________ cells (have a nucleus + organelles).
- There are about 200 different cell types in the human body, but they can be categorized into 2 major groups:
Eukaryotic
Behind the Biopsy
Regardless of type, all cells must reproduce (make copies of themselves)
- Why?
- How?
growth, replacing old or damaged cells
mitosis (division of nucleus) & cytokinesis (division of cellular contents)
Before mitosis...
- Chromosomes must ________________
- What is a chromosome?
Replicate
DNA wrapped around histone proteins (to prevents tangling). Contains genetic information in the form of genes. Humans have 46 chromosomes (23 pairs)
It's Your Turn! Mitosis
- In Schoology, open the Mitosis Assignment (2.2.1 folder)
- Review the attached Mitosis powerpoint and complete the handout.
- Fill in the blank
- Answer questions
- Draw the following in all stages of division:
- chromosomes
- centrioles
- spindle
Tumor formation
- Caused by ________________________________________
uncontrolled cell division
It's Your Turn!
Go to PLTW 2.1.5 > Division Gone Wrong
- Review the terms in the "Terminology - Tumors" table and take notes if needed
- Step 4 – write a paragraph with the terms
- Review the Biodigital interactive under "Types of Tissue"
- Complete the "Check for Understanding" at the bottom of this section
It's Your Turn!
- Examine Kai's biopsy and cytopathologist notes (2.1.5>Cellular Survey Says -> read note under the photo)
- Step 9 – revisit your differential diagnosis and discuss with your partner/group - make an official diagnosis
- Share your diagnosis with me
- Step 11 – research Kai's condition - use the NIH website
- What is the cause?
- Is it cancer?
- Is it inherited? Spontaneous?
- What are the major signs and symptoms?
- Potential severe complications?
- Treatments?