fleming
Aaron Schmitt
Created on October 23, 2024
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Alexander Fleming and antibiotics
Discoveries in biology
Savalle Anouk, Schmitt Aaron
wow
-Worked as a doctor during WWI
-Nobel prize of Medicine
-Scottish (born in Darvel)
-Doctor, biologist and pharmacist
-6th august 1881- 11th march 1955 (73 years old)
Alexander Fleming
disk diffusion test used for Staphylococcus aureus
Antibiotics
-type of antimicrobial substance active against bacteria.-produced by microorganisms (mostly bacteria and fungi)-not effective against viruses or fungi-greek roots: -"anti" = "against" -"bios" = "life"
Lysozyme crystals stained with methylene blue.
Lysozyme
-Antimicrobial enzyme produced by animals-Abundant in secretions including tears, saliva, human milk, and mucus -Discovered in 1921
fungal culture of Penicillium chrysogenum
Penicillin
-In 1928-Antibiotic obtained from Penicillium moulds-Its discovery increased life expectancy of 23 years-Kills bacteria by destroying their membrane
<- discovered how to isolate and concentrate the germ-killing agent in penicillin.
made it into a useful and effective drug, -> ten years after Fleming had abandoned its development
Ernst Chain
Howard Florey
Both received the nobel prize of medicine with Fleming
diagram detailling how bacteria become antibiotic resistant
Antibiotic resistance
-Overuse and misuse of antiobiotics-Could cause 10 millions deaths annually by 2050-Multiple contibuting factors-Due to mutations of the bacteria
Alexander Fleming’s discovery of penicillin revolutionized medicine, making fatal diseases treatable such as tuberculosis or pneumoniaIt is now commonly used in medicine, to a point where some bacterias developed a resistance to it.