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"CILLINS"AMINOGLYCOSIDE INACTIVATIONGRAM POSITIVE AND NEGATIVE

PENICILLINS

  • Cillin suffix
  • First antibiotic for clinical use, created from penicillin mold
  • Used in the treatment of gram positive and gram negative bacteria
  • Inactivation of parenteral

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BIRTH DEFECTSKIDNEY ALLERTKERNICTERUSFOLIC ACID SYNTHESIS

SULFONAMIDES

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  • Birth defects - Teratogenic
  • Kidney allert - Nephrotic Synderome
  • Kernicterus - bilirubin encephalopathy
  • Inhibits folic acid synthesis

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CyclinsTeeth and BonesYeast infections

Tetracyclines

  • Cyclines suffix
  • they accumulate in the teeth and bones, weakening the structure and causing staining and pitting of teeth and bones.
  • Superinfections like yeast infections

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TuberculosisLeprosyStains clothingLong treatment schedule.

Antimycobacterials

  • Anittuberculosis
  • Leprostatic
  • Discoloration of body fluids - tears, sweat, urine
    • Stains clothing
  • Long treatment schedule
    • 6mths to 2yrs
.

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"Mycins"Bacteriocidal or bacteriastaticPelvic inflammatory disease, upper respiratory infections, endocarditisQT interval prolongation

Macrolides

  • Mycins suffix
  • Bacteriocidal or bacteriastatic
  • Pelvic inflammatory disease, upper respiratory infections, endocarditis
  • QT interval prolongation

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VansQT interval prolongationTreatment of MRSA infectionsFoamy urine

Lipoglycopeptides

  • "Van" inside name
  • QT interval prolongation
    • Telavancin
  • Treatment of MRSA infections
  • Adverse effect of foamy urine

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SepticemiaSingle drug in classSynergistic effect with aminoglycosides

Monobactims

  • Septicemia
  • Single drug in class
    • Aztreonam
  • Synergistic effect with aminoglycosides

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ConsBacteriocidalParkinsonismOtotoxicity & nephrotoxicity

Aminoglycosoides

  • Cons suffix
  • Bacteriocidal
  • Parkinsonism
  • Ototoxicity & nephrotoxicity

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NEMSBACTERIOCIDALBETA-LACTAMSVALPORIC ACID

Carbapenems

  • "Nems" suffix
  • Bacteriocidal
  • Broad spectrum beta-lactams
  • Valporic acid - consider alternative treatment

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"Cefs"Multiple generationsBeta-lactams Bacteriostatic and BacteriocidalWarfin

Cephalosporins

  • "Cefs" prefix
  • Beta-lactams
  • Bacteriostatic and Bacteriocidal
  • Warfin - increased risk for bleeding

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Floxacins AnthraxTendon ruptureCorticosteroids

Fluroquinolons

  • "Floxacin" suffix
  • Post-exposure treatment of anthrax
  • Tendon rupture
    • Incressed risk with orticosteroid use

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