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"CILLINS"AMINOGLYCOSIDE INACTIVATION GRAM POSITIVE AND NEGATIVE

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PENICILLINS

• Cillin suffix
• First antibiotic for clinical use, created from penicillin mold
• Used in the treatment of gram positive and gram negative bacteria
• Inactivation of parenteral

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BIRTH DEFECTS KIDNEY ALLERT KERNICTERUS FOLIC ACID SYNTHESIS

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SULFONAMIDES

• Birth defects - Teratogenic
• Kidney allert - Nephrotic Synderome
• Kernicterus - bilirubin encephalopathy
• Inhibits folic acid synthesis

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Cyclins Teeth and Bones Yeast infections

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Tetracyclines

• Cyclines suffix
• they accumulate in the teeth and bones, weakening the structure and causing staining and pitting of teeth and bones.
• Superinfections like yeast infections

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Tuberculosis Leprosy Stains clothing Long treatment schedule.

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Antimycobacterials

• Anittuberculosis
• Leprostatic
• Discoloration of body fluids - tears, sweat, urine
• Stains clothing
• Long treatment schedule
• 6mths to 2yrs

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"Mycins" Bacteriocidal or bacteriastatic Pelvic inflammatory disease, upper respiratory infections, endocarditis QT interval prolongation

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Macrolides

• Mycins suffix
• Bacteriocidal or bacteriastatic
• Pelvic inflammatory disease, upper respiratory infections, endocarditis
• QT interval prolongation

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Vans QT interval prolongation Treatment of MRSA infections Foamy urine

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Lipoglycopeptides

• "Van" inside name
• QT interval prolongation
• Telavancin
• Treatment of MRSA infections
• Adverse effect of foamy urine

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Septicemia Single drug in class Synergistic effect with aminoglycosides

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Monobactims

• Septicemia
• Single drug in class
• Aztreonam
• Synergistic effect with aminoglycosides

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Cons Bacteriocidal Parkinsonism Ototoxicity & nephrotoxicity

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Aminoglycosoides

• Cons suffix
• Bacteriocidal
• Parkinsonism
• Ototoxicity & nephrotoxicity

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NEMSBACTERIOCIDALBETA-LACTAMSVALPORIC ACID

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Carbapenems

• "Nems" suffix
• Bacteriocidal
• Broad spectrum beta-lactams
• Valporic acid - consider alternative treatment

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"Cefs" Multiple generations Beta-lactams Bacteriostatic and Bacteriocidal Warfin

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Cephalosporins

• "Cefs" prefix
• Beta-lactams
• Bacteriostatic and Bacteriocidal
• Warfin - increased risk for bleeding

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Floxacins Anthrax Tendon rupture Corticosteroids

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Fluroquinolons

• "Floxacin" suffix
• Post-exposure treatment of anthrax
• Tendon rupture
• Incressed risk with orticosteroid use

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