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Methadone & Buprenorphine

XR Naltrexone

  • Longer length of treatment associated with better outcomes.
  • More data to support use of these medications.
  • Patients should continue as long as:
    • they benefit
    • have no contraindications

  • Limited data for long-term use of XR naltrexone (longest treatment arm in literature is 6 months).
  • Less data to support XR naltrexone, but useful in select patients.
  • Current recommendation is that patients should continue as long as:
    • they benefit
    • want to continue

MOUD Treatment Duration