Poland anomaly

Poland Anomaly

Start

Some hypotheses say that it could be caused by a disruption of blood flow during the embryonic state.

Origin

The origin is unknow. Indeed we know that is not inherited but no gene responsible has been identifided

Discovery :

It was named in 1962 by Patrick Clarkson, a plastic surgeon working at Guy's Hospital and Queen Mary's Hospital, London. He noticed that three of his patients had both a hand deformity and an underdeveloped breast on the same side. He discussed this with his colleague at Guy's Hospital, Dr Philip Evans, who agreed that the syndrome was "not widely appreciated". Clarkson found a reference to a similar deformity published by Alfred Poland, an English surgeon, over a hundred years earlier in Guy's Hospital reports, in 1841.

Sir Alfred Poland (30 August 1822 – 21 August 1872) was a 19th-century British surgeon. He is now best known for the first account of the condition later known as Poland syndrome,

Symptoms

Most of the people affected by the disease remain undiagnosted until puberty, when muscles begin to develop.

The Poland anomaly is caracterized by an underdevelopment and abnormalities of one side of the body, at the level of chest and arms muscles and bones.

Those physical issues aside, the illness do not generally cause any other health problem.

Here are the most frequent symptoms of the disease ->

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Distribution in the population

Men are more likely to be affected by the Poland anomaly, as two-thirds of the people having this disease are men.

In your opinion, what is the proportion of people who are affected by the Poland anomaly?

1 / 5000

1 / 20 000

1 / 30 000

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Traitements :

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Traitements:

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Hope you have learn more about the Poland anomaly !

Disruption of blood flow during the embryonic state

Disruption of blood flow during the embryonic state. This disruption is thought to occur around the sixth week of embryonic development and affects the blood vessels that will become the subclavian and vertebral arteries on each side of the body. The arteries normally supply blood to the embryonic tissues that give rise to the chest wall and hand on their respective sides. Variations in the site and extent of the disruption may explain the range of signs and symptoms that occur in Poland syndrome.