Thesis Outline Presentation

A History of Antipsychotics Nandini Vishwakarma

ChLorPromazine

Used to treat symptoms such as... Hallucinations Delusions Disordered thinking/speaking Behavior changes Social Withdrawals Suicidal thoughts (Schizophrenia, Bipolar, Acute Psychosis)

Antipsychotics: "A type of drug used to treat symptoms of psychosis [1].

AntiPsychotics

VI. Long Term Studies and OutcomesA. Efficacy Over Extended Periods B. Long Term Side Effects C. Comparative Long Term Studies VII. Impact on Current AntipsychoticsA. Influence on Drug Development B. Mechanistic Advancements C. Legacy in Psychiatric TreatmentVIII. Case Reports and Stories of ImpactA. Case Studies B. Personal Narratives IX. Comparative Analysis with other AntipsychoticsA. Efficacy of First and Second Generation Antipsychotics B. Cost-Effectiveness and Accessibility X. Future DirectionsA. Emerging Trends in Antipsychotics B. Innovations in Drug Delivery Systems

I. IntroductionA. Overview of ChlorpromazineB. Importance in Psychiatric TreatmentII. Historical Background Of ChlorpromazineA. Discovery and DevelopmentB. Early Clinical Trials and ApprovalsIII. Mechanism of ActionA. Pharmacodynamics B. Pharmacokinetics IV. Clinical UseA. Indications B. Administration and Dosage C. Efficacy in Symptoms Management V. Side Effects and Adverse ReactionsA. Common Side Effects B. Serious Adverse Reactions

Thesis Outline

References:

• https://www.cancer.gov/publications/dictionaries/cancer-terms/def/antipsychotic
• https://go.drugbank.com/drugs/DB00477
• https://www.sciencedirect.com/science/article/pii/B9780323998550000105

• https://www.cochrane.org/CD000284/SCHIZ_chlorpromazine-versus-placebo-schizophrenia
• https://news.feinberg.northwestern.edu/2023/07/27/antipsychotic-drugs-work-differently-than-scientists-believed/
• https://jeccr.biomedcentral.com/articles/10.1186/s13046-020-1534-z
• https://link.springer.com/article/10.1007/s40261-021-01001-0