Desert Island Escape

The Ewing DesertIsland

Escape room

Notebook

Notes about the island

Use with caution

Hey there, student doctor...

Welcome to your second to last SIGS case of the unit! Lucky you for stumbling upon this book.

This diary narrates the experiencesof a brave castaway who, after ending up on a remote island, faces a series of clever challenges to obtain the necessary resources to build a raft and be able to escape from this desolate island.Are you ready for this thrilling survival quest?

Tiririri-ri!

Backpack

Backpack

Plane

Shrubs

Forest

Raft

Shelter

Missions

Here's the roadmap you'll need.

Uh oh...

Are you lost?

1

Airplane

Luggage

mission

Backpack

Ewing sarcomas are most likely to present in which of the following patients?

A. 15 year old female

B. 15 year old male

C. 65 year old female

D. 65 year old male

mmm

Backpack

It will be added to your backpack.You will need it to be able to eat during the days you spend on the deserted island.

GOOD!

You have food and cooking utensils

Here you go!

Backpack

PAUSE! Discuss the following SO:

Identify the prevalence and risk factors of pediatric benign and malignant bone tumors

Plane

Shrubs

Forest

Raft

Shelter

Backpack

Missions

Let's go!

Logs

Forest

Backpack

Onto the next!

Woohoo!

2

mission

Backpack

Which of the following findings is unique to Ewing sarcomas?

D. Prominent nuclei on histostain

A. Increased WBC count

B. t(14;18) chromosomal translocation

C. t(11;22) chromosomal translocation

Will be added to your backpack.You will need it for the days you spend on the desert island.

GREAT!

You have a rope, maybe it will be useful for you

Great!

Backpack

PAUSE! Discuss the following SOs:

Research the concept of the Ewing Sarcoma family of tumors and why they tend to be viewed as a systemic diseaseDescribe the genetic etiology of Ewing SarcomaExplain the pathogenesis of Ewing Sarcoma

You're almost there!

Backpack

Plane

Shrubs

Forest

Raft

Shelter

Missions

Where to next?

Backpack

Food

Shrub

You're on a roll!

Almost there!

3

Mission

Backpack

A. Long bone diaphysis

B. Facial bones

C. Long bone epiphysis

D. Vertebrae

Where are Ewing sarcomas most likely to be found?

It will be added to your backpack.You will need it for the days you spend on the deserted island.

GOOD!

You have a hatchet, it might be useful to you

Keep it up!

Backpack

PAUSE! Discuss the following SO:

Identify pertinent +/- of clinical presentation and PE

Backpack

Airplane

Shrub

Forest

Raft

Shelter

Missions

Keep going!

Backpack

Tent

Shelter

You're amazing!

Almost to freedom!

4

Mission

A. CD50

B. CD98

C. CD99

Which membrane protein is highly expressed in Ewing sarcoma?

Backpack

D. CYP450

It will be added to your backpack.You will need it for the days you spend on the deserted island.

GOOD!

You have a flashlight, maybe it will be useful to you

There you go!

Backpack

PAUSE! Discuss the following SO:

Discuss pertinent...(a) Lab findings (i.e. elevated erythrocyte sedimentation rate, elevated lactate dehydrogenase)(b) Imaging (i.e. Xray, MRI, PET-CT)(c) Microscopic examination with H&E, immunohistochemical staining (i.e. CD99)

Uh oh!

One more question before you go...

Dangit

Backpack

A. Surgical resection

B. Chemotherapy drugs

C. Radiation therapy

Which of the following are NOT generally treatment/management options for Ewing Sarcoma?

D. Vitamin supplements

PAUSE! Discuss the following SOs:

Drug chart/discuss drug classes and mechanism of actions for vincristine, cyclophosphamide, doxorubicin, Ifosfamide-etoposideDiscuss significance of alternating cycles of chemotherapy drugsExplain surgery effects on the use of chemotherapies

NICE!

Now you can move on!

Backpack

Backpack

Airplane

Shrubs

Forest

Raft

Shelter

Missions

You've accomplished so much!

Wait, lookin your backpack

Check the items in your backpack and use the flashlight to find the code to access the final mission that will allow you to escape from the deserted island.

Keep searching

Code: SIGS

Keep searching

Keep searching

Keep searching

1st code: S

2nd code: I

3rd code: G

Raft

Logs

We're here!

You go girl

5

mission

Forest

Airplane

Mountains

Shelter

Shrubs

Where is your backpack?

You have explored the entire island, managed to build a raft, but now you can't remember where you left your backpack and you'll need it before you can leave. On the map, you can see the places where your backpack might be.

Drag the parts of the map to find where you left your backpack and be able to escape from the deserted island.

Deserted Island Map

Congratulations adventurer! You have shown great bravery and wit. You have successfully overcome each challenge and have managed to build the raft that will take you back to the civilized world. May your journey back be filled with new adventures and emotions!

CONGRATULATIONS!

Wow, you got it!

Missing SO's...

Missing SO's

Explain the importance of patient education for pediatric patients and familiesCompare and contrast imaging of benign and malignant tumors Justify image-guided biopsy in diagnosis

Ok! Run it back!

Don't give up!

Ouch!

even the greatest explorers faced unexpected challenges

Don't be discouraged, the adventure is not over yet! Take a moment to rest and try again. Remember every mistake is a learning opportunity that will bring you closer to victory. Cheer up, brave adventurer!

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Mission

Welcome to a new mission in our exciting adventure! In this challenging task, you will face unique obstacles that will test your wit and teamwork. Get ready to immerse yourself in a world full of mysteries and emotions, where every decision will bring you closer to victory.Let the survival begin!

A cool subtitle here

Mission

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Hint

In this window, you will find a series of key clues that will help you solve the challenges and puzzles that await you on this deserted island. Remember to keep your eyes wide open and work as a team to decipher each riddle.

Clue

In this window, you will find a series of key clues that will help you solve the challenges and riddles that await you on this deserted island. Remember to keep your eyes wide open and work as a team to decipher each puzzle.

Clue

Welcome to a new mission in our exciting adventure! In this challenging task, you will face unique obstacles that will test your wit and teamwork. Get ready to immerse yourself in a world full of mysteries and emotions, where every decision will bring you closer to victory.Let the survival begin!

A cool subtitle here

Mission