Janine's Medical Mystery

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Janine's Medical Mystery

Click "info" to watch a short video about antibiotic resistance.

Medical Mystery?

Meet Janine, a spirited 10th grader who lately, has been feeling off. What began as a simple sniffle quickly turned into something more serious. After visiting a doctor, she was handed a mysterious, bubbling solution and some surprising news: she has MRSA, a superbug. Janine needs your help to find a solution with her new solution!

Info

Introduction

Watch the video in the introduction! Then type MRSA to continue!

Visit 1

M1V1=M2V2

PV=NRT

Janine turns to WebMD and find that she has an antibitoic stock solution! We need to help her dilute this. What equation would we need to do a dilution?

1/3

Visit 1

(20µg/mL)(3mL)=(Xµg/mL)(100mL)

(100µg/mL)(XmL)=(3µg/mL)(20 mL)

(100µg/mL)(20mL)=(Xµg/mL)(3mL)

2/3

Great! We got it, we need to use the dilution equation. On the antibiotic stock solution we read that it has a concentration of 100 µg/mL. WebMD suggest we need a final concentration of 3 µg/mL and a final volume of 20 mL. How could we set-up this equation to find the missing volume?

(100µg/mL)(XmL)=(3µg/mL)(20 mL)

Visit 1

10 mL

0.6 mL

0.6 µg/mL

0.3 µg/mL

3/3

We're almost there. Solve for the missing volume!

Janine decides to test the 0.6 mL of the 3 µg/mL antibiotic solution on some of her cells before she takes it! And all her cells, good and bad, instantly... DIE!!!

Examine each doctor's treatment plan and determine which solution is best to cure Janine.

Doctor Visits

Dr. House

Dr. Grey

Dr. Pepper

WebMD

Visit 2

100 mL

0.1 mL

100 µg

Janine decide WebMD may not be the best solution. Her next visit is with Dr. Pepper. Dr.Pepper advises she use a different concentration! Calculate the new volume with the following information. M1 = 100 µg/mL V1 = x M2 = 0.5 µg/mL V2 = 20 mL

1/2

Visit 2

The infected cells would ALL be killed OVER TIME

The infected and good cells would ALL be killed

The infected cells would not be killed AT ALL

2/2

If 0.6 mL of 3 µg/mL was too strong of a concentration that killed all her cells, predict what would happen with 0.1 mL of 0.5 µg/mL

Examine each doctor's treatment plan and determine which solution is best to cure Janine.

Doctor Visits

Dr. House

Dr. Grey

Dr. Pepper

Web MD

Visit 3

Click here when completed with the reading

1/2

Knowing now that none of her infected cells would be killed, Janine has decided to visit the very well known Dr. Grey. She suggests you do some light reading on antibiotics

To make sure the antibiotics are strong enough to kill all the bacteria.

To ensure that the antibiotics are effective without harming the patient.

To make sure the antibiotics are affordable for everyone.

Visit 3

2/2

Why is it important for scientists to find the optimal concentration of antibiotics?

Examine each doctor's treatment plan and determine which solution is best to cure Janine.

Doctor Visits

Dr. House

Dr. Grey

Dr. Pepper

Web MD

V1 = 0.02 mL

V1 = 0.40 mL

V1 = 0.50 mL

V1 = 0.30 mL

Visit 4

D. (100µg/mL)(XmL)=(2.5µg/mL)(20 mL)

C. (100µg/mL)(XmL)=(2.0µg/mL)(20 mL)

B. (100µg/mL)(XmL)=(1.5µg/mL)(20 mL)

A. (100µg/mL)(XmL)=(0.1µg/mL)(20 mL)

Solution

Solución

continue

1/1

Janine now understand that she needs to find the optimal concentration and volume that won't kill all her cells, but in the correct amount of days will kill the bacteria. Her next doctor, Dr. House, suggest she calculate a few more concentrations and he can help her decide which is the best!

Start over?

Dr. House checked your calculations and determined that the 2.0µg/mL was the best concentration. Janine has been taking her antibiotics for 3 days and feels much better

CONGRATULATIONS

Oh oh!

But don't lose your balance, continue on your way and try again!

That answer is not correct...

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MRSA stands for methicillin-resistant Staphylococcus aureus. This bacterial infection is highly resistant to antibiotics (medicine). Watch the video to learn more.

4 - C

3 - B

2- D

1 - A