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Calpid D+ General

Cristina Martin Jime

Created on March 25, 2024

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Calpid D+

Excellence in bone health and performance for poultry

Conditions of use

Birth

What are we learning

Regulatory status

Trials

Hy D®

Calpid D+

Testimonials

Calcium pidolate

Uniqueness & synergy

BIRTH

From vets to vets

Pharmsure

Slate HallVeterinary Services

NUVAN

"It is the long history of humankind (and animal kind, too) that those who learned to collaborate and improvise most effectively have prevailed."

Charles Darwin

What is CalPid for?

  • For skeletal health, bone growth and eggshell quality
  • Use in drinking water as an intervention product

Vitamin Hy D® 25(OH)D3 & calcium pidolate

  • Active circulating form of Vitamin D, without the involvement of liver and hidrosulibility for a better Gastro Intestinal Tract (GIT) absorption
  • Ca molecule bound to two molecules of pidolic acid, precursor of arginine and proline, key components of bone and eggshell

Regulatory status

Vitamin D levels

Supplementing with CalPid, the vitamin D levels can be x100 higher than the relevant fixed maximum content in complete feed

CalPid is a complementary feed, which also falls into the category of feed intended for particular nutritional purposes.

What is a PARNUTs?"Feed intended for Particular Nutritional purposes"

It is feed which has a particular nutritional purpose which animals receive for their health.

EU 2020_354 Establishing a list of intended uses of feed for particular nutritional purposes and repealing Directive 2008_38_EC

EU 767_2009 Regulation on the placing on the market and use of feed

  • ‘Support for nutritional imbalances in dietary transition’
  • ‘2 to 15 days’
  • Concentration of legal maximum in complete feed:
  • > 100x
  • < 500x

Multiplication of additive in comparison to complete feed:

  • Normal complementary feed < 100x
  • Complementary feed for particular nutritional purpose > 100x

Hy D®

Vitamin Hy-D® 25(OH)D3 Active Vitamin D which provides a more potent approach compared to normal supplementation with vit D3, not involvement of liver and better GIT absorption

Standard vitamin D is untargeted

Calcium pidolate

Calcium pidolate Ca molecule bound to two molecules of pidolic acid, which increases the Ca absorption in the gut as a source of organic Ca, and acts as the substrate for the production of two key aminoacis, arginine and proline.

Synergy & UNIQUENESs

Calcium pidolate

HY D®

  • Not a source of calcium
  • Pidolic acid is the active substance, precursor of:
  • Arginine, fundamental building blocks for the manufacture of calcium transport proteins in enterocytes, calbindin
  • Proline, an essential component of the inner membrane of eggs and bones
  • More hydrophilic  higher GIT absorption
  • Liver not involved
  • Better absorption when bird is challenged (young, old, malabsorption, mycotoxicosis, stress, etc.)
  • Calcifediol is critical for Ca&P absorption and is a crucial substrate for skeletal and eggshell metabolism.
  • Key to entorcyte transport channel synthesis
  • Key to activate calbindin production
  • Stimulation of muscle cell growth

Uniqueness

Active and rapid absorption

x100 VitaminD

Innovative combination on the market

Maximum content

Calcium

Skeleton solidity & integrity

Challenged birds

Synergy

Best choice for birds under stress conditions

Activation of the factory engine supplying the needed building bricks

Conditions of use

Broilers

Layers/Breeders

What are we learning?

Lessons learned so far...

The solution

Use it early!

Dose

Diets

CalPid can be mixed even 24h pre application with no sedimentation issuesVery good solubility!

CalPid works better when first treatment is given during the first 5 to 7 days of life and skeletal development week 12-15

For broilers, two interventions of 40gr/1000 LBW shows the best results

Diets do not need to be modified, effects are improved when a correct vitamin D and diet is given

Trials

Locations

Europe

+registration on-going in Jordan & Israel

Layer farm, Portugal

Measurment of ionised calcium in serum after a 2 course intervention of CalPid D+

Broiler farm, Germany

Lameness history, obsverging Splayed leg issues on chickens

Higher BW at slaughter

Half leg culls

Lower mortality

UK trials

Trial 2

Trial 1

UK trials

In chicks, there are two critical phases of calcium need, so a two-intervention protocol was established: 1. The first intervention, from day 0 to 5, aims to support the deficiency of Vitamin D and available calcium during the first days, which is due to the decrease in Vitamin D levels absorbed from the yolk sac, combined with the low level of feed intake observed in chicks during their first week of life. 2. The second intervention, starting from the second week, is aimed at supporting the bird as its skeletal growth rate increases, especially after the dietary transition. The evaluation of tibial dyschondroplasia showed improved mineralisation and growth plate integrity at 21 days of age, supporting early use of the product.

The study revealed significant improvements in health and performance indicators in chickens, compared over an average of five production cycles : • Leg Health: 63% fewer discards due to lameness. • Antibiotic Use: 51% reduction. • Processing Rejections attributed to the farm: 29% reduction. • Tibial Dyschondroplasia: Incidence reduced by 50%. • Mortality Reduction: 32% decrease over five production cycles. • Economic Gain: 13% increase in financial return per square metre per week.

UK trials

Testimonials

"Great performance improvement leading to outstanding production numbers"

"Excellent bone strenght in broilers"

Big broiler integrationSpain

"New records for farm and the integration"

Broiler farmGermany

"No solubility problems or blockage of drinkers"

Testimonials

"Very fast response in animals"

"Reduction of rejections at slaughterhouse"

poultry Veterinary servicesUK

Thank you

Adrian Knoetze

BVSc MSc MRCVS

Clinical Director Atcham Slate Hall Veterinary Services

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