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Guess the Pattern - Week 2 - 2024
Melissa Cifuentes
Created on February 28, 2024
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Guess the ANA Pattern!
Punctate Nucleolar
Centromere
Speckled
Speckled
- The speckled pattern is the most commonly observed ANA pattern.
- Speckled pattern is distributed throughout the nucleus with areas varying in brightness and density. A clumpy speckled pattern may be seen with antibodies to n-RNP, Sm, and SSB/La.
- Speckled pattern may indicate various diseases, including lupus and Sjögren's Syndrome.
More aboutSjögren's Syndrome
Learn about theZEUS IFA ANA Solutions
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Sjögren's Syndrome
Sjögren's Syndrome is a chronic autoimmune disorder that happens when the immune system attacks the glands that make moisture in the eyes, mouth, and other parts of the body. The main symptoms are dry eyes and mouth, but other parts of the body may be affected as well, with many people reporting fatigue and joint and muscle pain. In addition, the disease can damage the lungs, kidneys, and nervous system. Sjögren’s syndrome predominantly affects women. Sjögren’s Syndrome can occur by itself or alongside other autoimmune conditions such as Rheumatoid Arthritis or Systemic Lupus Erythematosus.
https://www.niams.nih.gov/health-topics/sjogrens-syndrome
ZEUS IFA ANA Solutions
Antinuclear antibody (ANA) immunofluorescent testing aids in diagnosing lupus and monitors treatment progress through titer regression.* As a pioneer in immunofluorescence assay (IFA) technology, Sebia AI-ID has continually delivered quality and expertise in autoimmune serology that laboratories have relied upon since 1976. Our proprietary cell fixation process allows users to work with cells containing natural, unaltered antigens, resulting in simplified, easy-to-read patterns.
ZEUS dIFine System
Sebia Autoimmune & Infectious Diseases (Sebia AI-ID) is taking your ANA IFA testing to the next level by pairing our top tier IFA ANA HEp-2 slides with our dIFine® system, the next generation in IFA imaging and pattern recognition.