VIBRANT BREAKOUT

Innate Immunity Challenge

GO!

Index

Collect all the numbers by completing each of the challenges, and enter them in order in the final section to finish the game.

Introduction

Reward

01 Quiz

02 Find!

03 Correct image

04 Follow the series

start

QUIZ

Complete the following quiz, and getthe first number towards your reward!

QUIZ

question 1/5

What is innate immunity?

The response is very specific toward target

Third line of defence

Natural barriers (First line of defense) and inflammation (Second line of defense)

next

RIGHT!

QUIZ

Explanation:Barriers are the first line of defense against infection and tissue injury. It is broadly specific. The inflammatory response is the second line of defense and occurs as a response to tissue injury or infection, which is also nonspecific.

question 2/5

What cells are involved with innate barriers?

Epithelial Cells

T-lymphocytes,,B lympocytes

Mast cells, granulocytes (neutrophils, eosinophils, basophils), monocytes/macrophages, natural killer cells, platelets, endothelial cells

QUIZ

NEXT

RIGHT!

QUIZ

Explanation:

T-lymphocytes and B lymphocytes are part of adaptive immunity. Mast cells, granulocytes (neutrophils, eosinophils, basophils), monocytes/macrophages, natural killer cells, platelets, and endothelial cells are a part of the inflammatory response.

QUESTION 3/5

Mast cells macrophages, and dendritic cells

Somatic cell

QUIZ

When pathogen invasion or tissue damage occurs, inflammation is initiated by guardian cells. What are the guardian cells?

T cells and B cells

NEXT

RIGHT!

QUIZ

Explanation: Mast cells, macrophages, and dendritic cells are guardian cells

QUESTION 4/5

Which pathway activates the complement system?

Antigen body

Classical pathway, alternative pathway, and lectin pathway

Intrinsic pathway

QUIZ

NEXT

RIGHT!

QUIZ

Explanation:Antibodies activate the classical pathway. The alternative pathway is activated directly by substances found on the surface of infectious microorganisms. Alternative pathways are independent of antibodies and are activated by several plasma proteins.

QUESTION 5/5

Which function of the clotting system are exhibited at the site of injury or inflammation?

Prevents clot formation at the site of injury

Prevents the spread of infection to adjacent tissues

Vasodilation

QUIZ

NEXT

RIGHT!

QUIZ

Explanation:Other functions include stopping bleeding, helping prevent the spread of inflammation and infection, keeping the invader near the site of injury, maximizing the access of inflammatory cells and proteins, initiating the formation of two fibrinopeptide's that are released during the formation of fibrin and are chemotactic for neutrophils and increased vascular permeability and provide a framework for repair and healing.

Wrong!Lorem ipsum dolor sit amet, consectetuer adipiscing elit, sed diam nonummy nibh euismod tincidunt ut laoreet dolore magna aliquam erat volutpat.

ERROR!

TRY AGAIN

QUIZ

FIND!

From among all the statements you discover,click only on the correct ones

START

CLICK ONLY ON THE CORRECT STATEMENT 1/3

You can drag the light to search through the darkness

Mucus perspiration saliva tears and earwax are all examples of mechanical barriers

The innate immune response is slow

The complement system is redness, heat, swelling, and pain

Example of physical and mechanical barriers: Epithelial cells of the upper respiratory tract can trap microorganisms through the production of mucus and remove them through the action of hair-like cilia.

CLICK ONLY ON THE CORRECT STATEMENT 2/3

Which statement regarding mast cells is true?

Mast cells are found only in blood vessels.

Histamine causes vasoconstriction

Mast cells are not involved in allergic reactions.

Snake bites, bee venoms, and toxins may cause activation.

RIGHT!

CLICK ONLY ON THE CORRECT STATEMENT 3/3

Which receptor is expressed on macrophages and facilitates recognition and phagocytosis of bacterial pathogens?

Toll-like receptors

Pattern recognition receptors

Scavenger receptors

Complement receptors

RIGHT!

CLICK ONLY ON THE CORRECT STATEMENT 3/3

Which statement is true regarding neutrophils?

Neutrophils are agranular

Neutrophils enter the site of injury after lymphocytes and macrophages.

Neutrophils are the predominant phagocytes of early inflammation.

Neutrophils are the largest blood cells

RIGHT!

ERROR!

Wrong!That statement is incorrect

TRY AGAIN

CORRECT IMAGE

Choose the correct image

start

Which diagram DEMONSTRATES AN ACUTE INFLAMMATORY RESPONSE?

9

GREAT!

THE THIRD NUMBER IS:

BACK TO INDEX

START

serieS

Choose the correct shape in the series

WHAT biochemical messenger is produced by macrophages and lymphocytes in response to a bacterial pathogen?

Choose the correct shape:

?

Chemokines

Tumor necrosis factor

Interferons

Dendrites

Interleukins

Which complement factor is considered an anaphylatoxin?

Choose the correct shape:

?

C9

C7

C3a

C1

RIGHT!

2

GREAT!

THE FOURTH NUMBER IS:

BACK TO INDEX

7

GREAT!

THE FIRST NUMBER IS:

BACK TO INDEX

0

GREAT!

THE SECOND NUMBER IS:

BACK TO INDEX

ENTER THE SECRET CODE

Congratulations!

You've won the game!!!