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Nausea infographic

Anna Voit

Created on December 10, 2023

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Transcript

Mitigating Chemo induced Nausea

Nausea and vomitting are common side effects chemotherapy patients face during treatment. Designed to kill rapidly dividing cells, chemotherapy also kills cells that naturally divide rapidly. Such as the ones in the digestive tract and lining of the stomach.

Medical Marijuana

Delta-9-tetrahydocannabinol (THC) Cannabidiol (CBD) Effective, especially in cases where other antiemetic medications fail Psychoactive side effects & legal considerations

Dolasetron

5-HT3 receptor antagonist Effective for nausea in delayed phases Common side effects include headache, dizziness, constipation, diarrhea, anf fatigue

Ondansetron

Serotonin 5-HT3 receptor antagonist Generally effective, but varies between individuals Common side effects: headache, constipation, diarrhea, dizziness, fatigue

Aprepitant

Neurokinin (NK-1) receptor antagnoistsEffective in preventing nausea in the delayed phase Common side effects include fatigue, dizziness, constipation, diarrhea, headache

Metoclopramide

Dopamine receptor antagonist Effective through improving gastric emptying and reducing reflux Common side effects include drowsiness, restlessness, fatigue, diarrhea, and constipation

Granisetron

5-HT3 receptor antagonistEffective in delayed phases (24-120 hours after treatment) Common side effects include headache, dizziness, constipation, diarrhea, fatigue

Citations

Alexandra Griddine and Jeffery Bush, "Ondansetron," National Library of Medicine, 2023. American Cancer Society, "Marijuana and Cancer," 2022. DailyMed, "Granisetron," National Library of Medicine, 2023. Medline, "Dolasteron," US Dept of Health, 2018. Michael K. Ritchie and Arpan Kohli, "Aprepitant," National Library of Medicine, 2023. NCI, "Nausea and Vomiting Related to Cancer Treatment," US Dept of Health, 2023. Sasank Isola et al. "Metoclopramide," National Library of Medicine, 2023.