MICROPARTICLES PRESENTATION

Esther Lederberg

Yudy TavaresSemester 1 (Fall 2023)

START

Mayborn T. 2019 May 20. Esther Lederberg: A Forgotten Genius. Medium. https://medium.com/young-spurs/esther-lederberg-a-forgotten-genius-923f2ba1414f.

INDEX

Biography

Discoveries

Contributions

obstacles

Accomplishments

My opinion Sources

Thank you

Esther Lederberg Biography

• Esther Lederberg was born on December 18, 1922.
• She was born in New York during the great depression. She always had a big love for science.
• She graduated high school at just fifteen, got a bachelor's from Hunter College, and, went on to get her master's in genetics at Stanford University.
• She became a microbiologist
• she met her husband Joshua Lederberb At Stanford (he became a Molecular biologist)

Bio

Discoveries

• She discovered the lambda phage.
• Lambda phage is a virus that infects bacteria, specifically E coli.
• This discovery is important as researchers could observe how lambda phage interacts with the host, by doing so they can get an insight into crucial information such as replication, and expression of viral genes.

+ Transduction and Lambda Red Overview | GoldBio. goldbiocom. [accessed 2023 Dec 2]. https://goldbio.com/articles/article/Transduction-Lambda-Red-Overview.

Discoveries

• She continued making other contributions, such as the Lederberg technique, moderately known as replica plating.
• Replica planting is a technique that focuses on studying the genetic characteristics of bacteria, or when you are screening for certain mutations.

2022. Magazinesciencecom. https://www.magazinescience.com/en/biology/isolation-of-mutant-bacteria/?print=print.

Contributions

• The process of replica plants includes having a main plate with bacterial colonies growing on it.
• Picking up cells from the colony and moving them to a new plate where they transform and grow into new colonies.
• This technique helped scientists be able to screen bacterial colonies and help identify specific traits very quickly.

give an account of Lederberg’s replica plating experiment to show the genetic basis of evolution. wwwvedantucom. [accessed 2023 Dec 2]. https://www.vedantu.com/question-answer/give-an-account-of-lederbergs-replica-plating-class-12-biology-cbse-5fa8cbb9ce9ce85d09fa3eb8.

obstacles

• Although Esther Lederberg worked for more than 20 years, she was never given tenure.
• Esther's husband, Joshua Lederberb won a Nobel Prize for his contributions, despite that she contributed a lot that helped earn Joshua his recognition. The award went to him and two other male researchers; the academy did not recognize her effort (Zeldovich 2022).

Accomplishments

Esther Lederberg helped scientists be able to screen bacterial colonies and help identify specific traits very quickly; because of her inventions, many doors opened for the study of genetics.

Esther Lederberg's many discoveries, such as the lambda phage and the development of replica plating, were fundamental in providing more information about bacterial gene regulation

Esther Lederberg became a director of the plasmid reference center at Stanford in 1976.

My opinion

• I had never heard of Esther Lederberg and her accomplishments; I have heard of her husband, which shows how biased the science community can sometimes be.
• The project that fascinated me the most was her creation of the development replica.
• As a woman, the scientific community must continue evolving and become more accepting of women in STEM and not be so critical or biased. Everyone deserves equal opportunities and recognition.

sources

• Barron M. Esther Lederberg and the rise of microbial genetics. American Society for Microbiology. Published October 4, 2023.Available from:Esther Lederberg and the Rise of Microbial Genetics (asm.org)
• Steinmetz K. Esther Lederberg and her husband were both trailblazing scientists. Why have more people heard of him? New York Times. Published April 11, 2019. Available from:Why Don't We Remember More Trailblazing Women Scientists? | Time

Zeldovich L. Esther Lederberg changed our understanding of how bacteria breed. Published May 23, 2022. Available from:Esther Lederberg changed our understanding of how bacteria breed Popular Science (popsci.com)

THANK YOU!