Patho Proje

Addisons

• pathophysiology
• risk / signs/symptoms

• diagnosis
• medications
• nursing interventions
• if Unmedicated/Untreated

index

HPA Axis

Primary caused by autoimmunity Adrenal insufficiency, the symptoms of which result from hormonal deficiencies: glucocorticosteroids, mineralocorticosteroids and androgens

Pathophysiology

Adrenal cortex destruction, the body will not produce enough ACTH The body will attack the hormones Hypofunction on producing many hormones

Inside the body

Tempor Labore

Adrenal Glands

Gastro Issues

Hypotonia

Hyperpigmentation

• Hypotonia
• Weight loss

• Salt craving
• Gastrointestinal disorders
• Hyperpigmentation of the skin (vertilgo)
• Mucous membranes

SIGNS / Symptoms

What if?

Imaging

Sim Lab

Blood Test

Diagnosis

Hormonal Replacement

Medications

Hydrocortisone 3x-5x a day

Fludrocortisol (adjust meds by needs)

Prednisone or Dexamethasone

Assisting with ADL's

Interventions

Providing emotional support and providing education about the condition

Monitor Blood Pressure, Esp i it reports as low

Monitoring their intake of fluids and sodium to prevent dehydration

COMPLICATIONS

• Higher risk of death due to infections
• Cancer
• Cardiovascular causes
• Hypotension
• Shock
• Hypoglycemia
• Acute cardiovascular decompensation
• Death

thanks

The adrenal gland is told by ACTH to produce They will test how much cortisol is produce after a shot of ACTH

Simulation Test

Bilaterally on kidneys

Where they are located?

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HPA Axis

• Hypothalamus, Pitutary, Adrenal
• Hypofunction

They can test for certain levels of

• sodium
• potassium
• cortisol
• ACTH

Also testing for antibodies related to autoimmune Addisons

Blood Test

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Examples

Caused by mineralocorticoids not produced enough and potassium and sodium reintake causes issues in the intenstines

Gastro Disorders

• GERD
• IBS
• Ceciliac Disease

Irritable bowel syndrome (IBS) Small intestinal bacterial overgrowth (SIBO) Gastroesophageal reflux disease (GERD) Gallstones Celiac disease

Gastroinstential Issues

Weakness or lessened muscle tone

Hypotonia

They will look for the adrenal gland and analyze its physical size It will appear much smaller

Imaging