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V3- FINAL IMD QUIZ USA CONGRESSES

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How much do you know about Invasive Meningococcal Disease ?

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For use by Medical for scientific exchange and medical discussions only. Do not photograph, copy, or distribute.

The content contained in this presentation as developed by Sanofi for scientific exchange purposes and is not eligible for continuing medical education (CME) credit.

©2024 Sanofi. All rights reserved. v3.0 MAT-US-EXP 8/2026

MAT-US-2304881

question 1

Based on 2023 CDC data, MenACWY vaccination coverage rates are _____ for dose 1 and _____for dose 2.

A) 90%, 85%

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B) 75%, 80%

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D) 88%, 60%

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C) 95%, 90%

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Correct!

Correct answer : D

Per the latest data from the CDC, the vaccination coverage rate for dose one is 88% and for dose 2 is 60%

Reference: https://www.cdc.gov/mmwr/volumes/73/wr/mm7333a1.htm

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Incorrect!

Correct answer : D

Per the latest data from the CDC, the vaccination coverage rate for dose one is 88% and for dose 2 is 60%

Reference: https://www.cdc.gov/mmwr/volumes/73/wr/mm7333a1.htm

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question 2

Which serogroups have caused outbreaks reported in CDC health advisories during 2024 ?

B) B, C, Y

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A) A, B, W

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D) None of these

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C) C,W, Y

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Correct!

Correct answer : C

Serogroups C, W and Y. In 2024, CDC issued health advisories regarding IMD outbreaks that included cases caused by serogroups C,W and Y. Of note, a specific strain of the latter of which has proven unusually lethal, has led to the greatest number of reported cases. The outbreaks have had a disproportionate impact on Black or African American people, who have accounted for 63% of cases.

Reference: 1. Rubis, A ACIP June 28, 2024 https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2024-06-26-28/02-Mening-Rubis-508.pdf 2. CDC HAN Health Alert Network (HAN) - 00505 | Increase in Invasive Serogroup Y Meningococcal Disease in the United States (cdc.gov) 3. CDC HAN Health Alert Network (HAN) - 00508 | Meningococcal Disease Cases Linked to Travel to the Kingdom of Saudi Arabia (KSA): Ensure Pilgrims are Current on Meningococcal Vaccination (cdc.gov)

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Incorrect!

Correct answer : C

Serogroups C, W and Y. In 2024, CDC issued health advisories regarding IMD outbreaks that included cases caused by serogroups C,W and Y. Of note, a specific strain of the latter of which has proven unusually lethal, has led to the greatest number of reported cases. The outbreaks have had a disproportionate impact on Black or African American people, who have accounted for 63% of cases.

Reference: 1. Rubis, A ACIP June 28, 2024 https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2024-06-26-28/02-Mening-Rubis-508.pdf 2. CDC HAN Health Alert Network (HAN) - 00505 | Increase in Invasive Serogroup Y Meningococcal Disease in the United States (cdc.gov) 3. CDC HAN Health Alert Network (HAN) - 00508 | Meningococcal Disease Cases Linked to Travel to the Kingdom of Saudi Arabia (KSA): Ensure Pilgrims are Current on Meningococcal Vaccination (cdc.gov)

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question 3

Cases of disease due to serogroup B are increasing year upon year

True

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False

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Correct!

Correct answer : False

Epidemiology of serogroup B has not changed substantially, even after 2015, when ACIP recommended MenB vaccination for healthy adolescents on the basis of shared clinical decision making.

References 1. CDC Enhanced Meningococcal Disease Surveillance Report, 2016 https://www.cdc.gov/meningococcal/downloads/NCIRD-EMS-Report.pdf 2. CDC Enhanced Meningococcal Disease Surveillance Report, 2017 https://www.cdc.gov/meningococcal/downloads/NCIRD-EMS-Report-2017.pdf 3. CDC Enhanced Meningococcal Disease Surveillance Report, 2018 https://www.cdc.gov/meningococcal/downloads/NCIRD-EMS-Report-2018.pdf 4. CDC Enhanced Meningococcal Disease Surveillance Report, 2019 https://www.cdc.gov/meningococcal/downloads/NCIRD-EMS-Report-2019.pdf 5. CDC Enhanced Meningococcal Disease Surveillance Report, 2020 https://www.cdc.gov/meningococcal/downloads/NCIRD-EMS-Report-2020.pdf 6. CDC Enhanced Meningococcal Disease Surveillance Report, 2021 https://www.cdc.gov/meningococcal/downloads/NCIRD-EMS-Report-2021.pdf 7. CDC Enhanced Meningococcal Disease Surveillance Report, 2022 https://www.cdc.gov/meningococcal/downloads/NCIRD-EMS-Report-2022-508.pdf

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Incorrect!

Correct answer : False

Epidemiology of serogroup B has not changed substantially, even after 2015, when ACIP recommended MenB vaccination for healthy adolescents on the basis of shared clinical decision making.

References 1. CDC Enhanced Meningococcal Disease Surveillance Report, 2016 https://www.cdc.gov/meningococcal/downloads/NCIRD-EMS-Report.pdf 2. CDC Enhanced Meningococcal Disease Surveillance Report, 2017 https://www.cdc.gov/meningococcal/downloads/NCIRD-EMS-Report-2017.pdf 3. CDC Enhanced Meningococcal Disease Surveillance Report, 2018 https://www.cdc.gov/meningococcal/downloads/NCIRD-EMS-Report-2018.pdf 4. CDC Enhanced Meningococcal Disease Surveillance Report, 2019 https://www.cdc.gov/meningococcal/downloads/NCIRD-EMS-Report-2019.pdf 5. CDC Enhanced Meningococcal Disease Surveillance Report, 2020 https://www.cdc.gov/meningococcal/downloads/NCIRD-EMS-Report-2020.pdf 6. CDC Enhanced Meningococcal Disease Surveillance Report, 2021 https://www.cdc.gov/meningococcal/downloads/NCIRD-EMS-Report-2021.pdf 7. CDC Enhanced Meningococcal Disease Surveillance Report, 2022 https://www.cdc.gov/meningococcal/downloads/NCIRD-EMS-Report-2022-508.pdf

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question 4

According to the CDC, the duration following MenB vaccination is _______ , whereas the duration of protection following MenACWY vaccination is _______.

B) 3 to 4 years and 5 to 6 years

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A) 5 to7 years and 5 to 10 years

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C) 5 years and 5 years

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C) 1 to 2 years and 3 to <8 years

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Correct answer : C

Protection from MenB vaccine is estimated to wane substantially by 1-2 years postvaccination and protection from MenACWY is estimated to wane between 3 and <8 years post vaccination.

Reference: 1. Sarah Schillie Presentation, Feb 29, 2024 CDC Presentation https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2024-02-28-29/02-Meningitis-Schillie-508.pdf 2. NIS Teen 2023 Vaccination Coverage Among Adolescents Aged 13–17 Years — National Immunization Survey–Teen, United States, 2022 | MMWR (cdc.gov)

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Incorrect!

Correct answer : C

Protection from MenB vaccine is estimated to wane substantially by 1-2 years postvaccination and protection from MenACWY is estimated to wane between 3 and <8 years post vaccination.

Reference: 1. Sarah Schillie Presentation, Feb 29, 2024 CDC Presentation https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2024-02-28-29/02-Meningitis-Schillie-508.pdf 2. NIS Teen 2023 Vaccination Coverage Among Adolescents Aged 13–17 Years — National Immunization Survey–Teen, United States, 2022 | MMWR (cdc.gov)

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question 5

Which changes to the adolescent vaccination schedule are being considered by the ACIP this year?

A) Removing the routine MenACWY vaccination at age 11-12 years

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B) Making MenB vaccination a routine recommendation

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C) Both a and b

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Correct!

Correct answer : C

As of the February 2024 ACIP meeting, the Committee is considering five possible options for adolescent meningococcal vaccination:

  • Two of the five schedule options would remove the dose of MenACWY at age 11-12, three of the options would make MenB a routine vaccination and two would make MenB vaccination risk-based.

References1. Sarah Schillie Presentation, Feb 29, 2024 CDC Presentation https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2024-02-28-29/02-Meningitis-Schillie-508.pdf

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Incorrect!

Correct answer : C

As of the February 2024 ACIP meeting, the Committee is considering five possible options for adolescent meningococcal vaccination:

  • Two of the five schedule options would remove the dose of MenACWY at age 11-12, three of the options would make MenB a routine vaccination and two would make MenB vaccination risk-based.

References1. Sarah Schillie Presentation, Feb 29, 2024 CDC Presentation https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2024-02-28-29/02-Meningitis-Schillie-508.pdf

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“©2024 Sanofi. All rights reserved. MAT-US-2304881 v3.0 EXP 7/2025