Genetics Clinical Training

Genetics Clinical Training

Module 1: Genetics Overview

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Learning Objectives

Understand the history and fundamentals of genetics

Learn basics of genetic conditions, including inheritance patterns and types of genetic conditions

AGENDA

History and Building blocks of genetics: DNA, RNA, Protein

Types of Genetic Disorders

Important Terms

Introduction to Rare Disease

History and Building blocks of genetics

Question

The molecule of DNA was discovered byWatson and Crick in 1953.

False

True

DNA Discovery

James Watson, Francis Crick

FriedrichMiescher

Rosalind Franklin

Building Blocks:DNA --> RNA --> Protein

DNA: The blueprint for Life

Genetic code

Double helical structure

Comprised of sequence of bases

DNA bases code for "DNA words" in triplet

Deoxyribonucleic acid

Two linked strands that wind around each other as double helix

A, G, T, C

Each triplet codes for one amino acids

1. Held together by hydrogen bonds2. Resembles a twisted ladder

mRNA

Transcription: DNA --> mRNA

Ribonucleic Acid

Protein