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Economic Evaluation

ARC HEEE

Created on May 9, 2022

Economic Evaluation - Health Economics Resource

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Economic Evaluation

Welcome to the Applied Research Collaboration – Yorkshire and Humber (ARC YH) overview of economic evaluation of health and social care interventions. In this guide we aim to provide people who are new to the concept of economic evaluation in a health setting an intuitive guide of what the approach aims to achieve, and introduce some of the concepts and terminology you may come across.

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ARC HEEE research

Funders

ContacT

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This guide will take you through the intuition of economic evaluation, starting with why you might want to conduct an economic evaluation, and then exploring some of the possible approaches, or ‘frameworks’ to doing so.

Click on each topic to jump to it or press the next arrow to go through each in turn.

Who are we talking about?

What is the role of economic evaluation?

What is the aim of the different groups?

How might we value these different aims?

How do we estimate the cost of a treatment?

How do we value the things we have to stop doing?

But what about...?

Additional resources and information

How do we value health?

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The main principle of economic evaluation is we can't do it all. How do we measure the value of what we want to do, and what we have to stop in order to do it?

Cost

Benefit

How do we get the most from the limited resources we have?

Why do we value certain things?

What is the role of economic evaluation?

Economic evaluation aims to bring together all of the important questions that come to mind when we think about a number of competing options and which are the best. We focus on its use in health but it is relevant to decisions that involve trading off different options.

Whose value is it?

What is value?

What is the value of the other stuff that we can do if we do the new thing?

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Imagine you are a child and have 10 pence with which to buy sweets? You could buy the same 10 sweets every week

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Imagine a new sweet appears in the shop but costs 2p. You still only have 10p with which to buy sweets. How will you now spend your money?

Exchange money for sweets

1p sweets

2p sweets

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Now replace the sweets with healthcare. You still only have 10p to spend so you need to decide how you will spend your money?

Exchange money for healthcare

1p Healthcare

2p Healthcare

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Who are we talking about when we conduct an economic evaluation?

The first part of creating an economic evaluation is to be clear who it is aimed at informing, and who it is talking about. It is not always possible or practical to include everyone in the evaluation, although it is important to understand where groups may have different priorities and aims. In a health and social care setting it is accepted to aim to inform whoever pays for the treatment or activity being considered, with the patient or recipient being the group talked about.

Drag each group to where you think it belongs

Include

Exclude

Funders

Taxpayers

Patient

Families/carers

Public

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What is the aim of the different groups?

Once it has been decided who the economic evaluation will talk to and about, we need to consider what the aims of those groups is. Ultimately, we need to understand what we are trying to get the most or the least of. This can feel like a simple question, but often groups have different aims or more than one that might clash.

Drag each option in preference to the group you are thinking about

Most important aim

Least important aim

Minimising costs

Getting the most of source outcome

Creating a minimum standard

Saving lives

Fairness

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How might we value those different aims?

To conduct an economic evaluation we need to be able to measure the aims of each group, for example longer lives, better quality of life, economic growth.

Focus on your own personal values and drag each aim to include or exclude

Include

Long Life

Exclude

Healthy life

Fairness

Economic growth

Happiness

Wellbeing

Personal wealth

All of it

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How do we value health?

There are three ways in which we can value health, based on resources, clinical (biomarkers) and patient outcome measures. We use patient outcome measures in economic evaluations to represent the patient 'voice' as resources and clinical values don't.

Resources If you have a health condition it can lead to a visit to a hospital. The hospital may have an administrative target and may need to look at re-admissions or delayed transfers

Patient outcome measures We use outcome measures to represent the patient 'voice'. A patient is asked about their health over the last few weeks, focused on different areas e.g., mobility, self-care.

Clinical (biomarkers) You can look at someone’s blood sugars, their blood pressure or HIV CD-4 count. These are medical markers (values) of health.

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How do we estimate the cost of a treatment?

Things to consider

Consistent with the idea of a single health commissioner conventionally focus on costs to the NHS

Upfront cost of treatment

Split into 'resource use' and 'unit costs'

Long-term costs of care

'Resourse use'

How much of something a patient uses

'Unit cost'

The cost of each addtional bit of care provision

All other costs are put to one side

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How do we value the things we have to stop doing?

One way to think about it is to visualise a bookshelf . Each book represents a way to spend money on health. Each book has a health benefit and cost. The taller the book the more health benefit and the wider the book the more it costs. Rearrange the books on the shelf by replacing the books with new books. Ideally you want to remove the books with the greater cost and least health benefit.

Drag each book on to and off the bookshelf

Health benefit

Healthcare expenditure (cost)

Cost-effectiveness thresholds in health care: a bookshelf guide to their meaning and use. / Culyer, Tony. York, UK : Centre for Health Economics, University of York, 2015. p. 1-22 (CHE Research Paper; No. 121).

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But what about...?

Valuing different types of health

Inequality

Uncertainty

Different Decision Contexts

Valuing what we stop doing

Non-NHS costs

Comparing health

Non-health outcomes

End of life and fair innings

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Take away - Economic Evaluation basics

An Economic Evaluation aids decision making, it does not make it.

An Economic evaluation is not about valuing health or life, it is about getting the most of each for what the NHS has to spend.

An Economic Evaluation informs those paying for the treatment, with the patient being the group discussed.

Each Economic Evaluation potentially has a knock-on effect.

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Additional resources and information

Click on each topic to to find out about the additional resources and information available

Unlocking Real-World Data

Health Inequalities

Economic Evaluation In Practice

National ARC Shared Learning Event

YH ARC Resources

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Want to learn more about economic evaluation in practice?

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Economic evaluation in practice

Economic evaluation evidence for resource-allocation decision making: bridging the gap for local decision makers using English case studies – published within Applied Health Economics and Health Policy. DOI: https://doi.org/10.1007/s40258-022-00756-7

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Health Inequalities resources and information

Understanding and Addressing Inequalities: Sebastian Hinde – HSR UK Conference presentation of peer-reviewed publication (1). URL: https://www.youtube.com/watch?v=XL5ItvLmLVw

Health inequalities: to what extent are decision-makers and economic evaluations on the same page? Greg Fell talks to Seb Hinde and Dr Matt Franklin – available on Spotify or The University of Sheffield Player – ScHARR’s Communicable Research podcast, episode 11, of peer-reviewed paper (1). URL: https://player.sheffield.ac.uk/events/health-inequalities-what-extent-are-decisionmakers-and-economic-evaluations-same-page

Health inequalities: to what extent are decision-makers and economic evaluations on the same page? An English case-study – published within Applied Health Economics and Health Policy. DOI: https://doi.org/10.1007/s40258-022-00739-8

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Unlocking Real-World Data

Full report and supplementary material 1. Unlocking Data to Inform Public Health Policy and Practice: The Whole Collection – access to the report, supplementary material, and public briefing document. DOI: https://doi.org/10.15131/shef.data.c.6225912.v1

2. Unlocking Data to Inform Public Health Policy and Practice – the main report. DOI: https://doi.org/10.15131/shef.data.21221606.v1

3. Unlocking Data to Inform Public Health Policy and Practice: WP1 Mapping Review Supplementary Excel S1 – supplementary material for WP1. DOI: https://doi.org/10.15131/shef.data.21222272.v1

Online Blogs with hyperlinks 1. Unlocking real-world data to promote and protect health and prevent ill-health in the Yorkshire and Humber region – published via the Health Economics and Decision Science (HEDS) Blog. DOI: https://doi.org/10.15131/shef.data.14723685.v1

4. Data sharing between the NHS and councils to improve the health of local people– public briefing document. DOI: https://doi.org/10.15131/shef.data.21222239.v1

2. “It’s A Grey Area”: searching the grey literature on how local governments use real-world data – published via the HEDS Blog. DOI: https://doi.org/10.15131/shef.data.16644916.v1

3. Unlocking linked real-world data presents opportunities to improve public health – published via the London School of Economics (LSE) Impact Blog. URL: https://blogs.lse.ac.uk/impactofsocialsciences/2022/01/26/unlocking-linked-real-world-data-presents-opportunities-to-improve-public-health/

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Unlocking Real-World Data

Online Webinar or video with hyperlink1. An introduction to care metadata – published via the HEDS Blog and NIHR ARC-YH website/ newsletters. URL: https://digitalmedia.sheffield.ac.uk/media/Unlocking+data+-+an+introduction+to+care+metadata/1_29shr8vt

2. Understanding and Addressing Inequalities: Sebastian Hinde – HSR UK Conference presentation of peer-reviewed publication (1). URL: https://www.youtube.com/watch?v=XL5ItvLmLVw

NIHR ARC-YH Blogs with hyperlinks1. Unlocking real-world data to inform public health policy and practice – an introduction to care metadata – NIHR ARC-YH short blog which links to our online webinar (1). URL: https://www.arc-yh.nihr.ac.uk/news-events-and-media/news/unlocking-real-world-data-webinar-jan-2022

2. “It’s A Grey Area”: searching the grey literature on how local governments use real-world data – NIHR ARC-YH short blog which links to online blog (2). URL: https://www.arc-yh.nihr.ac.uk/news-events-and-media/news/its-a-grey-area-how-local-governments-use-data

3. Unlocking Data to Inform Public Health Policy and Practice – NIHR ARC-YH blog of our report’s plain English summary. URL: https://www.arc-yh.nihr.ac.uk/news-events-and-media/blogs/unlocking-data-to-inform-public-health-policy-and-practice

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National ARC Shared Learning Event

Watch a series of seven presentations featured at the, How Economic Evaluation Has Been Adapted for Service Delivery event, held in May 2022. The presentations feature: * Rachel Meacock, Senior Lecturer in Health Economics, The University of Manchester, ARC Greater Manchester. * Dr Matt Franklin, Senior Research Fellow, School of Health and Related Research, NIHR ARC Yorkshire & Humber. * Laura Bojke, Professor of Health Economics, Team for Economic Evaluation and Health Technology Assessment, Centre for Health Economics. * Sebastian Hinde, Research Fellow, Health Economics Equality and Evaluation theme, NIHR ARC Yorkshire and Humber * Chris Bojke, Professor of Health Economics, University of Leeds, NIHR ARC Yorkshire & Humber

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YH ARC Resources

Here are a range of resources, developed and/or sourced by the YH ARC Health Economics theme, including:

  • Checklist when planning an economic evaluation
  • Patient Reported Outcome Measures (PROMs) resource and checklist
  • Video explaining the EQ 5D in about two-and-a-half minutes
https://www.arc-yh.nihr.ac.uk/resources#h.p_mpzh-EFgITb7

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Contact details

Thank you for using this guide. Get in touch with us if you have any questions at ARC_HEEE@sheffield.ac.uk

Dr Matthew Franklin

Seb Hinde

https://www.york.ac.uk/che/staff/research/sebastian-hinde/ sebastian.hinde@york.ac.uk @sebh2005

https://www.sheffield.ac.uk/scharr/people/staff/matthew-franklin matt.franklin@sheffield.ac.uk @DrMattFranklin

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Contributors

Andy Tatttersall

Amanda Lane

Peter Murphy

https://www.york.ac.uk/crd/staff/peter-murphy/
https://www.sheffield.ac.uk/scharr/people/staff/andy-tattersall
https://www.sheffield.ac.uk/scharr/people/staff/amanda-lane

@Andy_Tattersall

@AJaneLane

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Our funders

https://www.arc-yh.nihr.ac.uk/

https://www.nihr.ac.uk/

@NIHR_ARC_YH

@NIHRresearch

The project is funded by NIHR Public Health Research (PHR), with in-kind support from the NIHR Applied Research Collaboration Yorkshire and Humber's Health Economics, Evaluation and Equality.

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Deciding cost-effectiveness

NICE

Checklist for planning Economic Evaluation

But what about...?

What is the NICE approach?

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Imagine you are the commissioner of healthcare in a public system looking to buy healthcare services for your population You need to consider 3 things

The cost to you of the drug the pharma company is hawking (compared to the generic that doesn’t come with a free pen and a sandwich platter)

What else you could spend it on ?

The amount of additional health benefit it is likely to entail (ideally not based on the company’s leaflet)

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If you only usually spend 1p on sweets and the new sweet costs 2p you will need to find the rest somewhere...

Exchange money for sweets

1p sweets

2p sweets

Menu

How do we value the things we have to stop doing?

One way to think about it is to visualise a bookshelf . Each book represents a possible way to spend money on health. For example, one book may be a new medicine for the population. Each has a health benefit and cost, the taller the book the more health benefit for each pound spent, the wider the book the more it costs in total. Rearrange the books on the shelf by replacing some of the books with new books. Ideally you want to remove the books with the greater cost and least health benefit.

Drag each book on to and off the bookshelf

Health benefit

Healthcare expenditure

Cost-effectiveness thresholds in health care: a bookshelf guide to their meaning and use. / Culyer, Tony. York, UK : Centre for Health Economics, University of York, 2015. p. 1-22 (CHE Research Paper; No. 121).

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