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pharmacology PRESENTATION

bishan singh

Created on May 7, 2022

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Transcript

Appetite stimulating & deprssing drugs

bishan singh slach,gp-14

Appetite

Appetite is the desire to eat food, sometimes due to hunger. Appealing foods can stimulate appetite even when hunger is absent, although appetite can be greatly reduced by satiety.

Hypothalamus

Ghrelin

  • Cholecystokinin
  • Oxyntomodulin
  • GLP-1
  • Peptide tyrosine-tyrosine (PYY)

Insulin &PP

pancreas

Leptin

adipocytes

mechanism of appetite

Benzodiazepine

Diazepam

Oxazepam

Cyproheptadine HCL

Cyproheptadine stimulates the appetite and promotes weights gain. Studies evaluating patients who take cyproheptadine for improving appetite indicate the medication can be a very effective appetite stimulant.

Few other Appetite stimulatingdrugs

Mirataz -undesired weight loss in cats. Mirataz, mirtazapine, is a prescription appetite stimulant for cats. Mirtazapine is an antidepressant type medication that works to increase appetite, support weight gain, and may reduce vomiting.Capromelin- a ghrelin receptor agonist and novel therapy for stimulation of appetite in dogs Glucocorticoids

Dirlotapide(slentrol)

It works as a gut-selective microsomal triglyceride transfer protein (MTTP or MTP) inhibitor. This blocks the assembly and release of lipoproteins into the bloodstream, thereby reducing fat absorption. It also elicits a satiety signal from lipid-filled cells lining the intestine.

Sources

  • https://pubmed.ncbi.nlm.nih.gov/29468076/
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530708/
  • https://pubmed.ncbi.nlm.nih.gov/25146662/
  • https://www.vetrxdirect.com/blog/mirataz-appetite-stimulant-for-cats/
  • https://todaysveterinarypractice.com/nutrition/dysrexia-dogs-cats/
  • https://docksci.com/pharmacological-appetite-stimulation-rational-choices-in-the-inappetent-ca
  • https://www.youtube.com/watch?v=NKjOfR8vcas&t=275s

thanks