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69504 - Essential Thrombocythaemia

PGLD

Created on April 28, 2021

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Bone marrow biopsy showing atypical megakaryocytes in a case of essential thrombocytosis. The atypical megakaryocytes are enlarged, mature with hyperlobulated nuclei. There is no significant increase in erythropoiesis or granulopoiesis.

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Bone marrow aspirate showing atypical megakaryocytes in a case of essential thrombocytosis. The atypical megakaryocytes are enlarged, with abundant mature cytoplasm and deeply lobed, hypersegmented (staghorn-like) nuclei.

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Peripheral blood smear in a case of essential thrombocytosis showing marked thrombocytosis. The platelets show anisocytosis and bizarre forms.