Testosterone:roles & Functions
Stefan Rankovic & Lowri Jenkins
What is testosterone?
Testosterone is an extremerly important sex hormone/primary androgen hormone. It holds many functions and roles in a mans body but is also existant in women. Testosterone links to cognition, bone health, growth, sexual reproduction and even aggression.
male aggression is most prevalent when testosterone levels are highest --Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
Understanding Testosterone
The process of testosterone conversion to dihyrdotestosterone
The binding of DHT to the androgen receptor
Freeform and bound testosterone can be found in the blood vessel
testosterone & Protein...
SHBG & Albumin binding to testosterone
The cell itself where the action takes place
This paragraph is ready to hold stunning creativity, experiences and stories.
The functions of testosterone
Functions of testosterone
Muscle Mass & Strength
the process of transcription, protein building and anti-cataboloistic function.
Behaviour
Agressive behaviours and outbursts.
Cognition
Memory, spacial abilities, facial recognition and verbal memory.
Mood- regulation and influence
Influence on depression and anxiety - but it does not directly impact it!
Influence on Women
excess body and facial hair
acne
decreased beast size
deepening of the voice
increased muscle mass
Influences on trans people
-takes years for full effects to be seen -response to hormones is more dependent on genetics-main areas affected:
- emotions
- sexuality
- reproduction
Disscussion
After learning about the physical effects of Testosterone on the human body what time period in a trans persons life do you feel it is most appropriate for them to begin hormone therapy?
Different ways testosteone is used medically
Physical aspects
Sexual Dysfunction
Prostate Cancer
muscles, bone density, heart
libido, erectile dysfunction
androgen deprivation therapy
References
Celec, P., Ostatníková, D., & Hodosy, J. (2015). On the effects of testosterone on brain behavioral functions. Frontiers in neuroscience, 9, 12. https://doi.org/10.3389/fnins.2015.00012
Berglund, L. H., Prytz, H. S., Perski, A., & Svartberg, J. (2011). Testosterone levels and psychological health status in men from a general population: the Tromsø study. The aging male : the official journal of the International Society for the Study of the Aging Male, 14(1), 37–41. https://doi.org/10.3109/13685538.2010.522276
Beauchet O. (2006). Testosterone and cognitive function: current clinical evidence of a relationship. European journal of endocrinology, 155(6), 773–781. https://doi.org/10.1530/eje.1.02306
Heany, Sarah J, van Honk, Jack, Stein, Dan J, & Brooks, Samantha J. (2016). A quantitative and qualitative review of the effects of testosterone on the function and structure of the human social-emotional brain. Metabolic Brain Disease, 31(1), 157–167. https://doi.org/10.1007/s11011-015-9692-y
Batrinos M. L. (2012). Testosterone and aggressive behavior in man. International journal of endocrinology and metabolism, 10(3), 563–568. https://doi.org/10.5812/ijem.3661
Testosterone, roles & functions
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Transcript
Testosterone:roles & Functions
Stefan Rankovic & Lowri Jenkins
What is testosterone?
Testosterone is an extremerly important sex hormone/primary androgen hormone. It holds many functions and roles in a mans body but is also existant in women. Testosterone links to cognition, bone health, growth, sexual reproduction and even aggression.
male aggression is most prevalent when testosterone levels are highest --Robert M. Sapolsky, Behave: The Biology of Humans at Our Best and Worst
Understanding Testosterone
The process of testosterone conversion to dihyrdotestosterone
The binding of DHT to the androgen receptor
Freeform and bound testosterone can be found in the blood vessel
testosterone & Protein...
SHBG & Albumin binding to testosterone
The cell itself where the action takes place
This paragraph is ready to hold stunning creativity, experiences and stories.
The functions of testosterone
Functions of testosterone
Muscle Mass & Strength
the process of transcription, protein building and anti-cataboloistic function.
Behaviour
Agressive behaviours and outbursts.
Cognition
Memory, spacial abilities, facial recognition and verbal memory.
Mood- regulation and influence
Influence on depression and anxiety - but it does not directly impact it!
Influence on Women
excess body and facial hair
acne
decreased beast size
deepening of the voice
increased muscle mass
Influences on trans people
-takes years for full effects to be seen -response to hormones is more dependent on genetics-main areas affected:
Disscussion
After learning about the physical effects of Testosterone on the human body what time period in a trans persons life do you feel it is most appropriate for them to begin hormone therapy?
Different ways testosteone is used medically
Physical aspects
Sexual Dysfunction
Prostate Cancer
muscles, bone density, heart
libido, erectile dysfunction
androgen deprivation therapy
References
Celec, P., Ostatníková, D., & Hodosy, J. (2015). On the effects of testosterone on brain behavioral functions. Frontiers in neuroscience, 9, 12. https://doi.org/10.3389/fnins.2015.00012 Berglund, L. H., Prytz, H. S., Perski, A., & Svartberg, J. (2011). Testosterone levels and psychological health status in men from a general population: the Tromsø study. The aging male : the official journal of the International Society for the Study of the Aging Male, 14(1), 37–41. https://doi.org/10.3109/13685538.2010.522276 Beauchet O. (2006). Testosterone and cognitive function: current clinical evidence of a relationship. European journal of endocrinology, 155(6), 773–781. https://doi.org/10.1530/eje.1.02306 Heany, Sarah J, van Honk, Jack, Stein, Dan J, & Brooks, Samantha J. (2016). A quantitative and qualitative review of the effects of testosterone on the function and structure of the human social-emotional brain. Metabolic Brain Disease, 31(1), 157–167. https://doi.org/10.1007/s11011-015-9692-y Batrinos M. L. (2012). Testosterone and aggressive behavior in man. International journal of endocrinology and metabolism, 10(3), 563–568. https://doi.org/10.5812/ijem.3661