Genetic Diseases Escape Room

Genetic Diseases

An Escape Room Adventure

click on the ghostto begin

By Donna Howell

Intro

Map

Introduction

Your mission is to complete 4 questions in each of the 4 levels to get to the end screen. When you get to the end screen, you will take a screenshot with your name showing and submit into Schoology for your grade!

WARNING: If you get an answer wrong, you start ALL OVER! WRITE ANSWERS DOWN AS YOU GO!

Back

Site Map

Mission 4

Mission 1

Mission 2

Mission 5

Mission 3

Mission 6

Site Map

Mission 4

Mission 1

Mission 2

Mission 5

Mission 3

Mission 6

Site Map

Mission 4

Mission 1

Mission 2

Mission 5

Mission 3

Mission 6

Site Map

Mission 4

Mission 1

Mission 2

Mission 5

Mission 3

Mission 6

Site Map

Mission 4

Mission 1

Mission 2

Mission 5

Mission 3

Mission 6

Site Map

Mission 4

Mission 1

Mission 2

Mission 5

Mission 6

Mission 3

Mission 1

Q3

Q1

Q2

Q4

Question 1

This condition is characterized by an accumulation of thick mucus in multiple organs including the lungs and pancreas. People with the condition often have chronic respiratory disease and digestive problems. What disease is this?

Maple Syrup Urine Disease

Cystic Fibrosis

Sickle Cell Anemia

Question 2

A pregnant woman has her fetal anatomy ultrasound at 20 weeks gestation, and her doctor tells her that her baby's arms and legs are shorter than expected. The femur and humerus measure less than the fifth percentile. Other ultrasound findings include a narrow thorax, a large head with a pronounced forehead, and hydrocephalus (increased fluid in the brain). What condition should the doctor inform the patient that her baby may have?

Treacher-Collins Syndrome

Achondroplasia

Trisomy 13

Question 3

Jordan, a 14-year-old male visits his doctor for a physical exam that is required by the basketball team prior to try outs. The basketball coach told Jordan he could be a great asset to the team because of his tall height. Jordan is already 6 foot 6 inches. In the medical history, the doctor learns that Jordan was diagnosed with dislocated lens of the eyes in the past year. During the physical exam, Jordan is noted to have unusually long fingers and a long arm span. He also has pectus excavatum (sunken chest). The doctor is suspicious of genetic disorder and sends him to a cardiologist who finds that Jordan has an enlarged aorta by echocardiography. What condition was the doctor suspicious of?

Marfan Syndrome

Tay-Sachs Disease

Long QT Syndrome

Question 4

What condition results in abnormally-shaped red blood cells, which can lead to anemia, fatigue, growth delay, jaundice, pain crises, frequent infections, pulmonary hypertension, and organ damage?

Sickle Cell Anemia

Hemophilia

Trisomy 16

Q3

Q1

Mission 2

Q2

Q4

Question 1

Common features of this condition are chorea (involuntary movements and jerks), poor coordination, impaired judgement, depression, and cognitive decline. Symptoms typically begin in a person's thirties or forties with death occurring 15 to 20 years after onset. Pathologically, there is an accumulation of abnormal protein in neurons, resulting in neuronal death in areas of the brain. What condition best fits with this description?

Huntington's Disease

Charcot-Marie-Tooth Disease

Myoclonic Epilepsy

Question 2

A 42-year-old pregnant woman goes in for her 20 week fetal anatomy ultrasound. Multiple major anomalies and soft markers are seen, including a heart defect, cleft lip, clenched hands, club feet, absent radial bones, growth restriction, and a small head size. The woman decides to have an amniocentesis. Fetal chromosome analysis came back abnormal. What condition does the baby most likely have?

Trisomy 18

Trisomy 16

Trisomy 21

Question 3

A pregnant woman receives her 20 week fetal anatomy ultrasound, which shows abnormal findings of the baby's skeleton. Multiple broken bones, limb shortening, and bowing of the bones are seen. Which condition should be included in the differential diagnosis?

Beckwith-Wiedemann Syndrome

Spina Bifida

Osteogenesis Imperfecta

Question 4

Kevin is a 11-year-old boy with progressive muscle weakness. His birth and newborn period were uncomplicated. In late infancy, Kevin started missing developmental milestones. His motor skills (sitting, standing, walking) were delayed. Symptoms critical to Kevin's diagnosis were calf enlargement, toe walking, and the Gowers' sign (a movement to standup where the child first places arms and knees on the ground and then moves the hands up the legs until an upright position is reached). What condition does Kevin most likely have?

Duchenne Muscular Dystrophy

Cerebral Palsy

Klinefelter Syndrome

Mission 3

Q3

Q1

Q4

Q2

Question 1

Which of the following is also known as "Royal Disease?"

Alzheimer's Disease

Sickle Cell Disease

Hemophilia

Question 2

What is the syndrome called where individual somatic cells contain three "X" chromosomes?

Turner Syndrome

Klinefelter Disease

Down Syndrome

Question 3

A man has enlarged breasts, spare hair on body and sex compliment XXY. What disorder does he have?

Turner Syndrome

Edward's Syndrome

Klinefelter Syndrome

Question 4

Colorblindness is due to a mutation on chromosome ____.

#12

#23

#7

Mission 4

Q3

Q1

Q4

Q2

Question 1

Two sex-linked recessive genetic disorders are:

Down syndrome & cystic fibrosis

Color blindness & sickle cell anemia

Color blindness & hemophilia

Question 2

On which popular show features an actor with cleidocranial dysplasia, who plays a character with the same rare disease?

Stranger Things

Peaky Blinders

The Office

Question 3

What is a primary malignant tumor of the skeleton characterized by the direct formation of immature bone or osteoid tissue by the tumor cells?

Abruzzo-Erickson Syndrome

Osteosarcoma

Biemond Syndrome

Question 4

In this disorder, a piece of chromosome #5 is missing. Children born with this disorder make a unique crying sound.

Prader-Willi Syndrome

Canavan Disease

Cri du Chat Syndrome

Mission 5

Q1

Q3

Q2

Q4

Question 1

A child goes to the bathroom, and the parents notice that his urine is unusually dark brown color. What genetic condition could the child have?

Coffin-Lowry Syndrome

Alkaptonuria

Galactosemia

Question 2

This genetic disorder primarily affects mostly Jewish people, and is characterized by destruction of nerve cells in the brain and spinal cord. What is it?

Wilson Disease

Tay-Sachs Disease

Joubert Syndrome

Question 3

If a child has a genetic disorder, and is uncharacteristically obese, what disorder might it be?

Hurler Syndrome

Feingold Syndrome

Prader-Willi Syndrome

Question 4

In Neimann-Pick disease, sphyngomyelin concentrates in a person's cells. In what exact structure in the cell does it accumulate?

Mitochondria

Lysosomes

Nucleus

Mission 6

Q1

Q3

Q4

Q2

Question 1

Which of the following is an autosomal dominant genetic disease?

Hemophilia

Noonan Syndrome

Cystic Fibrosis

Question 2

Which of the following conditions is NOT one found on the X chromosome?

Alport Syndrome

Alcardi Syndrome

Hunter Syndrome

Question 3

In the genetic disorder Thalassemia, what protein is produced in an abnormal form?

Hemoglobin

Fibrinogen

Albumin

Question 4

Suppose you are looking at a person who has acromegaly. What would you see?

They have microcephaly

They are very tall

They have melanin spots on their skin

Pull your name down from the apple in upper left corner, and take a screenshot of this screen MAKING SURE YOUR NAME SHOWS! UPLOAD IN SCHOOLOGY.

2Click on the picture to go back