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The Untold History of DNA

Katlyn Paslawski

Created on August 10, 2020

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Transcript

The Untold History of DNA

How the term "Dexyribose Nucleic Acid" came to be

Observed leucocytes from the pus on fresh surgical bandages (Dahm, 2004).

Noticed a substance precipitated when an acid was added to the solution. He called his substance Nuclein (Dahm, 2004).

Due to the presence inside the nucleus, Miescher called it Nuclein (Dahm, 2004).

FRIEDRICH MIESCHER

I shall call it Nuclein!

1869

Friedrich Miescher

"Nuclein"

1889

Richard Altmann

"Nucleic Acid"

Renamed Nuclein to Nucleic Acid after Albrecht Kossel's discovery that nucleic acids are the bases that make up what is now called DNA (Aliouche, 2019).

Levene discovered DNA found from thymus (now called Thymine) after Kossel's discovery (Frixione & Ruiz-Zamarripa, 2019).

Phoebus Levene

1908

Phoebus Levene

"Thymus Nucleic Acid"

His discovery led to the name change from Thymus Nucleic Acid to Desoxy-Ribose Nucleic Acid (Frixione & Ruiz-Zamarripa, 2019).

1929

Phoebus Levene

"Desoxy-Ribsose Nucleic Acid"

Levene discovered Ribose, the sugar component of DNA that he referred to at the time as d-ribose (Frixione & Ruiz- Zamarripa, 2019).

1953

Watson and Crick

"Deoxyribose Nucleic Acid"

Started using deoxyribose nucleic acid (D.N.A) in their publications on the double helix structure of DNA (Aliouche, 2019).

Watson and Crick

References

Aliouche, H. (May 1, 2019). History of DNA research: Scientific pioneers & their discoveries. News Medical. Retrieved from https://www.news-medical.net/life-sciences/History-of-DNA-Research-Scientific-Pioneers-Their-Discoveries.aspx Dahm, R. (2004). Friedrick Miescher and the discovery of DNA. Developmental Biology. 278, 274-288. Frixione, E., & Ruiz-Zamarripa, L. (2019). The “scientific catastrophe” in nucleic acids research that boosted molecular biology. Journal of Biological Chemistry, 294, 2249-2255.