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HTLV-1 Genome Dashboard
Khouri Lab
Created on August 6, 2020
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Transcript
hTLV-1 genome dashboard
Click on the red button next to the genomic region to access the information
We started with the characterization of hbz genomic region as a part of our study.
HTLV-1 Genome Dashboard is a tool created with the purpose of reuniting the information of the HTLV-1 genome.
We intend to feed this dashboard in the future with information on the other genomic regions in order to characterize the whole genome.
8702
3'LTR
8652
8301
9055
8881
8653
8882
374
HBZ SI
5'LTR
8690
7290
6686
HBZ
7312
6686
pX
env
pol
pro
gag
23
8382
6686
6669
5203
5210
2778
1960
2113
824
777
603
375
604
Download the complete .xlsx file
The reading frame of hbz gene is reverse (3’-5’) but the standard notation of DNA sequences is from 5’ to 3’.Therefore, HBZ protein is encoded by the antisense strand of HTLV-1 proviral genome.
80160 240 320 400 480 560
181 161 241 321 401 481 561
HBZ: 7312-6686
Most frequent non-synonymous mutations
aminoacid
nucleotide
TTGCAACCACATCGCCTCCAGCCTCCCCTGCCAATAATTAACCTCTCCCATCAAATCCTCCTTCTCCTGCAGCAACTTCCTCCGTTCAGCCTCCAAGGACTCCACCTCGCCTTCCAACTGTCTAGTATAGCCATCAATCCCCAACTCCTGCATTTTTTCTTTCCTAGCACTATGCTGTTTCGCCTTCTCAGCCCCTTGTCTCCACTTGCGCTCACGGCGCTCCTGCTCTTCCTGCTTCCTCCTAGCGACGTCAGCGGCCTTCTTCTCCGCCCGCCTCCTGCGCCGTGCCTTCTCCTCTTCCTTCCTTTTCAAATACTCAGCGGTCTGCTTTTCCTCCTCTTTCTCCCGCTCTTTTTTTCGCTTCCTCTTCTCCTCAGCCCGTCGCTGCCGATCACGATGCGTTTCCCCGCGAGGTGGCGCTTTCTCCCCTGGAGGGCCCCGTCGCAGCCGGCCGCGGCTTTCCTCTTCTAAGGATAGCAAACCGTCAAGCACAGCTTCCTCCTCCTCCTTGTCCTTTAACTCTTCCTCCAAGGATAATAGCCCGTCCACCAATTCCTCCACCAGCAGGTCCTCCGGGCATGACACAGGCAAGCATCGAAACAGCCCTGCAGATACAAAGTTAACCAT
HBZ SI
HBZ
hTLV-1 genome dashboard hbz
HBZ SI
HBZ
Home
TTGCAACCACATCGCCTCCAGCCTCCCCTGCCAATAATTAACCTCTCCCATCAAATCCTCCTTCTCCTGCAGCAACTTCCTCCGTTCAGCCTCCAAGGACTCCACCTCGCCTTCCAACTGTCTAGTATAGCCATCAATCCCCAACTCCTGCATTTTTTCTTTCCTAGCACTATGCTGTTTCGCCTTCTCAGCCCCTTGTCTCCACTTGCGCTCACGGCGCTCCTGCTCTTCCTGCTTCCTCCTAGCGACGTCAGCGGCCTTCTTCTCCGCCCGCCTCCTGCGCCGTGCCTTCTCCTCTTCCTTCCTTTTCAAATACTCAGCGGTCTGCTTTTCCTCCTCTTTCTCCCGCTCTTTTTTTCGCTTCCTCTTCTCCTCAGCCCGTCGCTGCCGATCACGATGCGTTTCCCCGCGAGGTGGCGCTTTCTCCCCTGGAGGGCCCCGTCGCAGCCGGCCGCGGCTTTCCTCTTCTAAGGATAGCAAACCGTCAAGCACAGCTTCCTCCTCCTCCTTGTCCTTTAACTCTTCCTCCAAGGATAATAGCCCGTCCACCAATTCCTCCACCAGCAGGTCCTCCGGGCATGACACAGGCAAGCATCGAAACAGCCCTGAGGCCGCCAT
The reading frame of hbz gene is reverse (3’-5’) but the standard notation of DNA sequences is from 5’ to 3’.Therefore, HBZ protein is encoded by the antisense strand of HTLV-1 proviral genome.
HBZ SI
80160 240 320 400 480 560
181 161 241 321 401 481 561
HBZ
HBZ SI: 7290-6686 + 8702-8690
HBZ SI
HBZ
hbz
aminoacid
nucleotide
hTLV-1 genome dashboard
Home
hbz
50100 150 200
151 101 151 201
HBZ
MVNFVSAGLFRCLPVSCPEDLLVEELVDGLLSLEEELKDKEEEEAVLDGLLSLEEESRGRLRRGPPGEKAPPRGETHRDRQRRAEEKRKRKKEREKEEEKQTAEYLKRKEEEKARRRRRAEKKAADVARRKQEEQERRERKWRQGAEKAKQHSARKEKMQELGIDGYTRQLEGEVESLEAERRKLLQEKEDLMGEVNYWQGRLEAMWLQ
HBZ
HBZ
aminoacid
nucleotide
RRERKWRQGAE
DOMAINS
HBZ SI
KRKEEEKARRRRRAEKKAADVARRK
LRRGPPGEKAPPRGETHRDRQRRAEEKRKRKKEREKEE
HBZ
EKQTAEYLKRKEEEKARRRRRAEKKAADVARRKQEEQERRERKWRQGAE
PTMS
HBZ SI
MOTIFS
HBZ
hTLV-1 genome dashboard
KAKQHSARKEKMQELG
Home
hbz
GRLEAMWLQ
IDGYTRQLEGEVESLEAERRKLLQEKEDLMGEVNYWQ
QTAEYLKRKEEEKARRRRRAEKKAADVARRKQEEQERRERKWRQGAEKAKQHSARKEKMQELG
LRRGPPGEKAPPRGETHRDRQRRAEEKRKRKKEREKEEEK
MVNFVSAGLFRCLPVSCPEDLLVEELVDGLLSLEEELKDKEEEEAVLDGLLSLEEESRGR
50100 150 200
151 101 151 201
HBZ
DOMAINS
HBZ
HBZ
aminoacid
nucleotide
hTLV-1 genome dashboard
HBZ SI
RRERKWRQGAE
KRKEEEKARRRRRAEKKAADVARRK
HBZ
LRRGPPGEKAPPRGETHRDRQRRAEEKRKRKKEREKEE
EKQTAEYLKRKEEEKARRRRRAEKKAADVARRKQEEQERRERKWRQGAE
PTMS
HBZ SI
MOTIFS
HBZ
KAKQHSARKEKMQELG
Home
hbz
RRRRR
50100 150 200
151 101 151 201
HBZ
HBZ
MOTIFS
aminoacid
nucleotide
hTLV-1 genome dashboard
VDGLL
HBZ
LDGL
KRKRKK
EQERRE
MVNFVSAGLFRCLPVSCPEDLLVEELVDGLLSLEEELKDKEEEEAVLDGLLSLEEESRGRLRRGPPGEKAPPRGETHRDRQRRAEEKRKRKKEREKEEEKQTAEYLKRKEEEKARRRRRAEKKAADVARRKQEEQERRERKWRQGAEKAKQHSARKEKMQELGIDGYTRQLEGEVESLEAERRKLLQEKEDLMGEVNYWQGRLEAMWLQ
HBZ SI
DOMAINS
RRERKWRQGAE
KRKEEEKARRRRRAEKKAADVARRK
HBZ
LRRGPPGEKAPPRGETHRDRQRRAEEKRKRKKEREKEE
EKQTAEYLKRKEEEKARRRRRAEKKAADVARRKQEEQERRERKWRQGAE
PTMS
HBZ SI
HBZ
KAKQHSARKEKMQELG
Home
hbz
THR
SLEE
50100 150 200
151 101 151 201
HBZ
HBZ
HBZ
PTMS
aminoacid
nucleotide
hTLV-1 genome dashboard
SLEE
SCPE
GLFRCL
GAEKAK
LEGEVESLEAERRKLLQEKEDL
SAR
MVNFVSAGLFRCLPVSCPEDLLVEELVDGLLSLEEELKDKEEEEAVLDGLLSLEEESRGRLRRGPPGEKAPPRGETHRDRQRRAEEKRKRKKEREKEEEKQTAEYLKRKEEEKARRRRRAEKKAADVARRKQEEQERRERKWRQGAEKAKQHSARKEKMQELGIDGYTRQLEGEVESLEAERRKLLQEKEDLMGEVNYWQGRLEAMWLQ
RRERKWRQGAE
HBZ SI
DOMAINS
KRKEEEKARRRRRAEKKAADVARRK
LRRGPPGEKAPPRGETHRDRQRRAEEKRKRKKEREKEE
HBZ
EKQTAEYLKRKEEEKARRRRRAEKKAADVARRKQEEQERRERKWRQGAE
HBZ SI
MOTIFS
HBZ
KAKQHSARKEKMQELG
Home
HBZ SI
DOMAINS
HBZ
PTMS
HBZ SI
MOTIFS
HBZ
hbz
50100 150 200
151 101 151 201
HBZ SI
MAASGLFRCLPVSCPEDLLVEELVDGLLSLEEELKDKEEEEAVLDGLLSLEEESRGRLRRGPPGEKAPPRGETHRDRQRRAEEKRKRKKEREKEEEKQTAEYLKRKEEEKARRRRRAEKKAADVARRKQEEQERRERKWRQGAEKAKQHSARKEKMQELGIDGYTRQLEGEVESLEAERRKLLQEKEDLMGEVNYWQGRLEAMWLQ
HBZ SI
HBZ
aminoacid
nucleotide
hTLV-1 genome dashboard
Home
HBZ SI
HBZ
PTMS
HBZ SI
MOTIFS
HBZ
hbz
EAMWLQ
YTRQLEGEVESLEAERRKLLQEKEDLMGEVNYWQGRL
EYLKRKEEEKARRRRRAEKKAADVARRKQEEQERRERKWRQGAEKAKQHSARKEKMQELGIDG
GPPGEKAPPRGETHRDRQRRAEEKRKRKKEREKEEEKQTA
MAASGLFRCLPVSCPEDLLVEELVDGLLSLEEELKDKEEEEAVLDGLLSLEEESRGRLRR
50100 150 200
151 101 151 201
HBZ SI
DOMAINS
HBZ SI
HBZ
aminoacid
nucleotide
hTLV-1 genome dashboard
Home
HBZ SI
DOMAINS
HBZ
PTMS
HBZ SI
HBZ
hbz
RRRRR
EQERRE
KRKRKK
50100 150 200
151 101 151 201
HBZ SI
MOTIFS
HBZ SI
HBZ
aminoacid
nucleotide
hTLV-1 genome dashboard
VDGLL
LDGLL
MAASGLFRCLPVSCPEDLLVEELVDGLLSLEEELKDKEEEEAVLDGLLSLEEESRGRLRRGPPGEKAPPRGETHRDRQRRAEEKRKRKKEREKEEEKQTAEYLKRKEEEKARRRRRAEKKAADVARRKQEEQERRERKWRQGAEKAKQHSARKEKMQELGIDGYTRQLEGEVESLEAERRKLLQEKEDLMGEVNYWQGRLEAMWLQ
Home
DOMAINS
HBZ SI
HBZ
PTMS
HBZ SI
MOTIFS
HBZ
hbz
THR
50100 150 200
151 101 151 201
HBZ SI
HBZ SI
HBZ
aminoacid
nucleotide
hTLV-1 genome dashboard
SL
SCPE
EE
SCPE
SLEE
GLFRCL
GAEKAK
LEGEVESLEAERRKLLQEKEDL
AR
MAASGLFRCLPVSCPEDLLVEELVDGLLSLEEELKDKEEEEAVLDGLLSLEEESRGRLRRGPPGEKAPPRGETHRDRQRRAEEKRKRKKEREKEEEKQTAEYLKRKEEEKARRRRRAEKKAADVARRKQEEQERRERKWRQGAEKAKQHSARKEKMQELGIDGYTRQLEGEVESLEAERRKLLQEKEDLMGEVNYWQGRLEAMWLQ
Home